TY - JOUR
T1 - Controversies Surrounding Critical Care Nutrition
T2 - An Appraisal of Permissive Underfeeding, Protein, and Outcomes
AU - Patel, Jayshil J.
AU - Martindale, Robert G.
AU - McClave, Stephen A.
N1 - Publisher Copyright:
© 2017 American Society for Parenteral and Enteral Nutrition
PY - 2018/3
Y1 - 2018/3
N2 - Over the past few years, numerous studies have called into question the optimal dose, timing, composition, and advancement rate of nutrition during the early acute phase of critical illness. These studies suggest permissive underfeeding with slow advancement may be more beneficial than aggressive full feeding. These counterintuitive results were possibly explained by enhanced autophagy, less hyperglycemia, or prevention of refeeding syndrome. This review underscores the controversies surrounding permissive underfeeding, aims to answer whether permissive underfeeding is appropriate for all critically ill patients, describes the impact of optimal protein delivery on critical care outcomes, discusses nutrition risk, and cogitates on the impact of nutrition on critical care outcomes.
AB - Over the past few years, numerous studies have called into question the optimal dose, timing, composition, and advancement rate of nutrition during the early acute phase of critical illness. These studies suggest permissive underfeeding with slow advancement may be more beneficial than aggressive full feeding. These counterintuitive results were possibly explained by enhanced autophagy, less hyperglycemia, or prevention of refeeding syndrome. This review underscores the controversies surrounding permissive underfeeding, aims to answer whether permissive underfeeding is appropriate for all critically ill patients, describes the impact of optimal protein delivery on critical care outcomes, discusses nutrition risk, and cogitates on the impact of nutrition on critical care outcomes.
KW - hypocaloric feeding
KW - nutrition risk
KW - permissive underfeeding
KW - trophic feeding
UR - http://www.scopus.com/inward/record.url?scp=85044066169&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85044066169&partnerID=8YFLogxK
U2 - 10.1177/0148607117721908
DO - 10.1177/0148607117721908
M3 - Review article
C2 - 28742432
AN - SCOPUS:85044066169
SN - 0148-6071
VL - 42
SP - 508
EP - 515
JO - Journal of Parenteral and Enteral Nutrition
JF - Journal of Parenteral and Enteral Nutrition
IS - 3
ER -