Coronary artery bypass grafting in Native Americans: A higher risk of death compared to other ethnic groups?

Brahmajee K. Nallamothu, Sanjay Saint, Som Saha, A. Mark Fendrick, Keith Kelley, Scott D. Ramsey

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


BACKGROUND: While the efficacy and safety of coronary artery bypass grafting (CABG) has been established in several clinical trials, little is known about its outcomes in Native Americans. MEASUREMENTS AND MAIN RESULTS: We assessed clinical outcomes associated with CABG in 155 Native Americans using a national database of 18,061 patients from 25 non-governmental, not-for-profit U.S. health care facilities. Patients were classified into five groups: 1) Native American, 2) white, 3) African American, 4) Hispanic, and 5) Asian. We evaluated for ethnic differences in in-hospital mortality and length of stay, and after adjusting for age, gender, surgical priority, case-mix severity, insurance status, and facility characteristics (volume, location, and teaching status). Overall, we found the adjusted risk for in-hospital death to be higher in Native Americans when compared to whites (odds ratio [OR], 3.8; 95% confidence interval [CI], 1.5 to 9.8), African Americans (OR, 3.4; 95% CI, 1.1 to 9.9), Hispanics (OR, 7.1; 95% CI, 2.5 to 20.3), and Asians (OR, 2.8; 95% CI, 1.1 to 7.0). No significant differences were found in length of stay after adjustment across ethnic groups. CONCLUSIONS: The risk of in-hospital death following CABG may be higher in Native Americans than in other ethnic groups. Given the small number of Native Americans in the database (n = 155), however, further research will be needed to confirm these findings.

Original languageEnglish (US)
Pages (from-to)554-559
Number of pages6
JournalJournal of general internal medicine
Issue number8
StatePublished - 2001


  • Coronary artery bypass grafting
  • Coronary artery disease
  • Ethnicity
  • Native Americans
  • Race

ASJC Scopus subject areas

  • Internal Medicine


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