Correlation of bioscintigraphy, contrast venography, and iodine-125 fibrinogen uptake test

G. L. DeNardo, S. J. DeNardo, R. F. Carretta, H. G. Bogren, A. L. Jansholt, K. A. Krohn, N. F. Peek

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


In 40 patients believed to have deep venous thrombosis, bioscintigrams performed with I-123 fibrinogen were available for comparison with either contrast venograms of I-125 fibrinogen uptake tests. If either contrast venography or the fibrinogen uptake test was accepted as a standard for comparison, the accuracy of bioscintigraphic imaging was 90%. Most discrepancies between the procedures could be interpreted as due to heparin treatment, although bioscintigrams often were positive in patients treated with heparin for a short interval of time. Additionally, bioscintigrams provided information to distinguish venous thrombosis from other sources for local accumulation of radioactivity. Bioscintigraphy seems to be a promising noninvasive method for the detection of deep venous thrombosis of the lower extremities.

Original languageEnglish (US)
Pages (from-to)880-883
Number of pages4
JournalClinical Nuclear Medicine
Issue number12
StatePublished - 1985
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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