TY - JOUR
T1 - Cost-effectiveness of private umbilical cord blood banking
AU - Kaimal, Anjali J.
AU - Smith, Catherine C.
AU - Laros, Russell K.
AU - Caughey, Aaron B.
AU - Cheng, Yvonne W.
PY - 2009/10
Y1 - 2009/10
N2 - OBJECTIVE:: To investigate the cost-effectiveness of private umbilical cord blood banking. METHODS:: A decision-analytic model was designed comparing private umbilical cord blood banking with no umbilical cord blood banking. Baseline assumptions included a cost of $3,620 for umbilical cord blood banking and storage for 20 years, a 0.04% chance of requiring an autologous stem cell transplant, a 0.07% chance of a sibling requiring an allogenic stem cell transplant, and a 50% reduction in risk of graft-versus-host disease if a sibling uses banked umbilical cord blood. RESULTS:: Private cord blood banking is not cost-effective because it cost an additional $1,374,246 per life-year gained. In sensitivity analysis, if the cost of umbilical cord blood banking is less than $262 or the likelihood of a child needing a stem cell transplant is greater than 1 in 110, private umbilical cord blood banking becomes cost-effective. CONCLUSION:: Currently, private umbilical cord blood banking is cost-effective only for children with a very high likelihood of needing a stem cell transplant. Patients considering private blood banking should be informed of the remote likelihood that a unit will be used for a child or another family member.
AB - OBJECTIVE:: To investigate the cost-effectiveness of private umbilical cord blood banking. METHODS:: A decision-analytic model was designed comparing private umbilical cord blood banking with no umbilical cord blood banking. Baseline assumptions included a cost of $3,620 for umbilical cord blood banking and storage for 20 years, a 0.04% chance of requiring an autologous stem cell transplant, a 0.07% chance of a sibling requiring an allogenic stem cell transplant, and a 50% reduction in risk of graft-versus-host disease if a sibling uses banked umbilical cord blood. RESULTS:: Private cord blood banking is not cost-effective because it cost an additional $1,374,246 per life-year gained. In sensitivity analysis, if the cost of umbilical cord blood banking is less than $262 or the likelihood of a child needing a stem cell transplant is greater than 1 in 110, private umbilical cord blood banking becomes cost-effective. CONCLUSION:: Currently, private umbilical cord blood banking is cost-effective only for children with a very high likelihood of needing a stem cell transplant. Patients considering private blood banking should be informed of the remote likelihood that a unit will be used for a child or another family member.
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U2 - 10.1097/AOG.0b013e3181b8fc0d
DO - 10.1097/AOG.0b013e3181b8fc0d
M3 - Article
C2 - 19888044
AN - SCOPUS:70349659485
SN - 0029-7844
VL - 114
SP - 848
EP - 855
JO - Obstetrics and gynecology
JF - Obstetrics and gynecology
IS - 4
ER -