Cowper's gland hyperplasia: A potential pitfall at MRI of the prostate

Omar Kamal, Bryan R. Foster, Kevin Turner, Sadhna Verma, Sungmin Woo, Tharakeswara K. Bathala, Fergus V. Coakley

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


MRI features are presented in a multicenter retrospective series of five patients with a unilateral masslike lesion seen in the genitourinary diaphragm at MRI performed for known or suspected prostate cancer. In all cases, the lesion appeared as an encapsulated 1.3 to 3.0 cm mass of heterogeneous low or intermediate T2 signal intensity in the genitourinary diaphragm, and targeted biopsy demonstrated benign Cowper's gland tissue. This entity is a potential imaging pitfall that could result in a diagnosis of an exophytic nodule of benign prostatic hyperplasia or local spread of prostate cancer. We present these cases to facilitate correct identification of Cowper's gland hyperplasia as an occasional finding at MRI of the prostate.

Original languageEnglish (US)
Pages (from-to)337-340
Number of pages4
JournalClinical Imaging
StatePublished - Nov 2021


  • Cowper's glands
  • MRI
  • Prostate

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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