"Crystal Dex:" Free-Base Dextromethorphan

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Dextromethorphan (DXM) is a common component of combination cold medications that has become a popular drug of abuse for young adults. Abusers of DXM have developed a simple acid-base extraction technique to "free-base," or extract, the DXM from the unwanted guaifenesin, coloring agents, sweeteners, and alcohol that are typically included in combination cold preparations. We report a case of DXM overdose after ingestion of this purified "Crystal Dex" and discuss the "Agent Lemon" and single-phase extraction techniques that are used to free-base the dextromethorphan.

Original languageEnglish (US)
Pages (from-to)393-396
Number of pages4
JournalJournal of Emergency Medicine
Issue number4
StatePublished - May 2007


  • crystal
  • dextromethorphan
  • emergency medicine
  • free-base
  • overdose
  • toxicity

ASJC Scopus subject areas

  • Emergency Medicine


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