Crystal Structures of Aspartate Carbamoyltransferase Ligated with Phosphonoacetamide, Malonate, and CTP or ATP at 2.8-Å Resolution and Neutral pH

Medicine & Life Sciences

• phosphonoacetamide 100%
• Aspartate Carbamoyltransferase 67%
• malonic acid 60%
• Cytidine Triphosphate 54%
• Allosteric Site 27%
• Hydrogen Bonding 23%
• pyrimidine 19%
• purine 13%
• Nitrogen 11%
• Phosphates 6%
• Oxygen 5%
• Ribose 5%
• triphosphoric acid 4%
• Hydrogen 4%
• Hydroxyl Radical 4%
• Catalytic Domain 3%
• Binding Sites 2%

Chemical Compounds

• Aspartate 42%
• Pyrimidine 19%
• Crystal Structure 19%
• Amino Groups 18%
• Hydrogen Bond 16%
• Purine 16%
• pH Value 16%
• Nitrogen 9%
• Molecular Replacement 6%
• Quaternary Structure 6%
• Ribose 6%
• Trimer 5%
• Dioxygen 5%
• Binding Site 3%
• Hydrogen 2%