TY - JOUR
T1 - Cytoarchitecture and saccular innervation of nucleus Y in the mouse
AU - Frederickson, Christopher J.
AU - Trune, Dennis R.
PY - 1986/10/15
Y1 - 1986/10/15
N2 - The cytoarchitecture and saccular innervation of the mouse nucleus y were investigated by using Golgi, Nissl, and myelin stains and anterograde axonal transport of horseradish peroxidase. Nucleus y was found to be a compact group of cells in a small fiber‐free region dorsal to the restiform body. Qualitative and morphometric analyses showed that most (75%) of the nucleus y neurons could not be reliably subdivided into morphologic subgroups, but varied continuously in soma size (15–25 μm), shape (fusiform to stellate), and number of dendrites (two to four), and had sparsely branched dendrites with an average of 3 to 4 spines per 10 μm of length. Three groups of cells that were identified morphometrically accounted for 10% (type I: large stellate cells), 9% (type II: long‐dendrite cells), and 6% (type III: elongated soma cells) of the y neurons. Vestibular nerve axons transporting horseradish peroxidase after injury at their origin in the saccular neuroepithelium were found to form a dense terminal meshwork that was virtually co‐extensive with the cytoarchitectonic boundaries of nucleus y. Nucleus y was distinguished from the overlying infracerebellar nucleus on the basis of anatomical, cytoarchitectural, and hodological features.
AB - The cytoarchitecture and saccular innervation of the mouse nucleus y were investigated by using Golgi, Nissl, and myelin stains and anterograde axonal transport of horseradish peroxidase. Nucleus y was found to be a compact group of cells in a small fiber‐free region dorsal to the restiform body. Qualitative and morphometric analyses showed that most (75%) of the nucleus y neurons could not be reliably subdivided into morphologic subgroups, but varied continuously in soma size (15–25 μm), shape (fusiform to stellate), and number of dendrites (two to four), and had sparsely branched dendrites with an average of 3 to 4 spines per 10 μm of length. Three groups of cells that were identified morphometrically accounted for 10% (type I: large stellate cells), 9% (type II: long‐dendrite cells), and 6% (type III: elongated soma cells) of the y neurons. Vestibular nerve axons transporting horseradish peroxidase after injury at their origin in the saccular neuroepithelium were found to form a dense terminal meshwork that was virtually co‐extensive with the cytoarchitectonic boundaries of nucleus y. Nucleus y was distinguished from the overlying infracerebellar nucleus on the basis of anatomical, cytoarchitectural, and hodological features.
KW - Golgi
KW - HRP
KW - morphometrics
KW - otolithic organ
KW - vestibular nuclei
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U2 - 10.1002/cne.902520303
DO - 10.1002/cne.902520303
M3 - Article
C2 - 3793979
AN - SCOPUS:0023023109
SN - 0021-9967
VL - 252
SP - 302
EP - 322
JO - Journal of Comparative Neurology
JF - Journal of Comparative Neurology
IS - 3
ER -