Dancing with the host: Flow-dependent bacterial adhesion

Ralph R. Isberg, Penelope Barnes

Research output: Contribution to journalReview articlepeer-review

80 Scopus citations

Abstract

Most bacteria that colonize eukaryotes must bind directly to host cells to establish a replicative niche. In enteric bacteria, adhesion to host cells is often promoted by a lectin found on surface-localized pili. Some pili promote efficient adhesion only when they are subjected to shear stress, as found during the flow of blood over endothelium or mucous over the surface of the epithelium.

Original languageEnglish (US)
Pages (from-to)1-4
Number of pages4
JournalCell
Volume110
Issue number1
DOIs
StatePublished - Jul 12 2002
Externally publishedYes

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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