Dancing with the host: Flow-dependent bacterial adhesion

Ralph R. Isberg; Penelope Barnes

doi:10.1016/S0092-8674(02)00821-8

Dancing with the host: Flow-dependent bacterial adhesion

Ralph R. Isberg, Penelope Barnes

Research output: Contribution to journal › Review article › peer-review

80 Scopus citations

Abstract

Most bacteria that colonize eukaryotes must bind directly to host cells to establish a replicative niche. In enteric bacteria, adhesion to host cells is often promoted by a lectin found on surface-localized pili. Some pili promote efficient adhesion only when they are subjected to shear stress, as found during the flow of blood over endothelium or mucous over the surface of the epithelium.

Original language	English (US)
Pages (from-to)	1-4
Number of pages	4
Journal	Cell
Volume	110
Issue number	1
DOIs	https://doi.org/10.1016/S0092-8674(02)00821-8
State	Published - Jul 12 2002
Externally published	Yes

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1016/S0092-8674(02)00821-8

Cite this

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title = "Dancing with the host: Flow-dependent bacterial adhesion",

abstract = "Most bacteria that colonize eukaryotes must bind directly to host cells to establish a replicative niche. In enteric bacteria, adhesion to host cells is often promoted by a lectin found on surface-localized pili. Some pili promote efficient adhesion only when they are subjected to shear stress, as found during the flow of blood over endothelium or mucous over the surface of the epithelium.",

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N2 - Most bacteria that colonize eukaryotes must bind directly to host cells to establish a replicative niche. In enteric bacteria, adhesion to host cells is often promoted by a lectin found on surface-localized pili. Some pili promote efficient adhesion only when they are subjected to shear stress, as found during the flow of blood over endothelium or mucous over the surface of the epithelium.

AB - Most bacteria that colonize eukaryotes must bind directly to host cells to establish a replicative niche. In enteric bacteria, adhesion to host cells is often promoted by a lectin found on surface-localized pili. Some pili promote efficient adhesion only when they are subjected to shear stress, as found during the flow of blood over endothelium or mucous over the surface of the epithelium.

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Dancing with the host: Flow-dependent bacterial adhesion

Abstract

ASJC Scopus subject areas

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