TY - JOUR
T1 - Development and implementation of a prescription opioid registry across diverse health systems
AU - Ray, G. Thomas
AU - Altschuler, Andrea
AU - Karmali, Ruchir
AU - Binswanger, Ingrid
AU - Glanz, Jason M.
AU - Clarke, Christina L.
AU - Ahmedani, Brian
AU - Andrade, Susan E.
AU - Boscarino, Joseph A.
AU - Clark, Robin E.
AU - Haller, Irina V.
AU - Hechter, Rulin
AU - Roblin, Douglas W.
AU - Sanchez, Katherine
AU - Yarborough, Bobbi Jo
AU - Bailey, Steffani R.
AU - McCarty, Dennis
AU - Stephens, Kari A.
AU - Rosa, Carmen L.
AU - Rubinstein, Andrea L.
AU - Campbell, Cynthia I.
N1 - Publisher Copyright:
© 2022 The Author(s). Published by Oxford University Press on behalf of the American Medical Informatics Association.
PY - 2022/7/1
Y1 - 2022/7/1
N2 - Objective: Develop and implement a prescription opioid registry in 10 diverse health systems across the US and describe trends in prescribed opioids between 2012 and 2018. Materials and Methods: Using electronic health record and claims data, we identified patients who had an outpatient fill for any prescription opioid, and/or an opioid use disorder diagnosis, between January 1, 2012 and December 31, 2018. The registry contains distributed files of prescription opioids, benzodiazepines and other select medications, opioid antagonists, clinical diagnoses, procedures, health services utilization, and health plan membership. Rates of outpatient opioid fills over the study period, standardized to health system demographic distributions, are described by age, gender, and race/ethnicity among members without cancer. Results: The registry includes 6 249 710 patients and over 40 million outpatient opioid fills. For the combined registry population, opioid fills declined from a high of 0.718 per member-year in 2013 to 0.478 in 2018, and morphine milligram equivalents (MMEs) per fill declined from 985 MMEs per fill in 2012 to 758 MMEs in 2018. MMEs per member declined from 692 MMEs per member in 2012 to 362 MMEs per member in 2018. Conclusion: This study established a population-based opioid registry across 10 diverse health systems that can be used to address questions related to opioid use. Initial analyses showed large reductions in overall opioid use per member among the combined health systems. The registry will be used in future studies to answer a broad range of other critical public health issues relating to prescription opioid use.
AB - Objective: Develop and implement a prescription opioid registry in 10 diverse health systems across the US and describe trends in prescribed opioids between 2012 and 2018. Materials and Methods: Using electronic health record and claims data, we identified patients who had an outpatient fill for any prescription opioid, and/or an opioid use disorder diagnosis, between January 1, 2012 and December 31, 2018. The registry contains distributed files of prescription opioids, benzodiazepines and other select medications, opioid antagonists, clinical diagnoses, procedures, health services utilization, and health plan membership. Rates of outpatient opioid fills over the study period, standardized to health system demographic distributions, are described by age, gender, and race/ethnicity among members without cancer. Results: The registry includes 6 249 710 patients and over 40 million outpatient opioid fills. For the combined registry population, opioid fills declined from a high of 0.718 per member-year in 2013 to 0.478 in 2018, and morphine milligram equivalents (MMEs) per fill declined from 985 MMEs per fill in 2012 to 758 MMEs in 2018. MMEs per member declined from 692 MMEs per member in 2012 to 362 MMEs per member in 2018. Conclusion: This study established a population-based opioid registry across 10 diverse health systems that can be used to address questions related to opioid use. Initial analyses showed large reductions in overall opioid use per member among the combined health systems. The registry will be used in future studies to answer a broad range of other critical public health issues relating to prescription opioid use.
KW - EHR data
KW - opioid use disorder
KW - prescription opioids
KW - registry
UR - http://www.scopus.com/inward/record.url?scp=85134999583&partnerID=8YFLogxK
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U2 - 10.1093/jamiaopen/ooac030
DO - 10.1093/jamiaopen/ooac030
M3 - Article
AN - SCOPUS:85134999583
SN - 2574-2531
VL - 5
JO - JAMIA Open
JF - JAMIA Open
IS - 2
M1 - ooac030
ER -