TY - JOUR
T1 - Diffuse Idiopathic Skeletal Hyperostosis and Its Relation to Back Pain Among Older Men
T2 - The MrOS Study
AU - Holton, Kathleen F.
AU - Denard, Patrick J.
AU - Yoo, Jung U.
AU - Kado, Deborah M.
AU - Barrett-Connor, Elizabeth
AU - Marshall, Lynn M.
PY - 2011/10
Y1 - 2011/10
N2 - Objectives: To estimate the prevalence of diffuse idiopathic skeletal hyperostosis (DISH) in a cross-sectional study of elderly men age 65 to 100 years and to examine back and neck pain as possible correlates of DISH. Methods: DISH was defined using Resnick's criteria and scored according to Mata on lateral spine radiographs of 298 randomly selected participants from the MrOS Study. Standardized self-reported questionnaires were used to assess the frequency and severity of back and neck pain, and the relation of these to DISH status was estimated with X 2 tests, as well as prevalence ratios and 95% confidence intervals using log-binomial regression models. Results: DISH was observed in 126 older men (42%), increased with age (30%, 39%, 48%, and 56% for ages 65-69, 70-74, 75-79, and ≥80 respectively), and was positively associated with body mass index (BMI) (P = 0.04) and blood pressure (P = 0.02). Significantly less back pain in the past 12 months was reported among men with DISH as compared to men without (59% vs 71%, P = 0.03), which remained after adjustment for age, BMI, and blood pressure (prevalence ratios = 0.73, 95% confidence interval = 0.57-0.95). Back pain severity (P = 0.07) and frequency (P = 0.06) were also less frequent among men with DISH compared to men without, whereas reported neck pain was similar between groups (P = 0.39). Conclusions: Among community-dwelling elderly men, DISH prevalence is high, increases with age, and is positively associated with BMI and blood pressure. Frequency of self-reported back pain over the past 12 months was lower in older men with DISH as compared to those without DISH.
AB - Objectives: To estimate the prevalence of diffuse idiopathic skeletal hyperostosis (DISH) in a cross-sectional study of elderly men age 65 to 100 years and to examine back and neck pain as possible correlates of DISH. Methods: DISH was defined using Resnick's criteria and scored according to Mata on lateral spine radiographs of 298 randomly selected participants from the MrOS Study. Standardized self-reported questionnaires were used to assess the frequency and severity of back and neck pain, and the relation of these to DISH status was estimated with X 2 tests, as well as prevalence ratios and 95% confidence intervals using log-binomial regression models. Results: DISH was observed in 126 older men (42%), increased with age (30%, 39%, 48%, and 56% for ages 65-69, 70-74, 75-79, and ≥80 respectively), and was positively associated with body mass index (BMI) (P = 0.04) and blood pressure (P = 0.02). Significantly less back pain in the past 12 months was reported among men with DISH as compared to men without (59% vs 71%, P = 0.03), which remained after adjustment for age, BMI, and blood pressure (prevalence ratios = 0.73, 95% confidence interval = 0.57-0.95). Back pain severity (P = 0.07) and frequency (P = 0.06) were also less frequent among men with DISH compared to men without, whereas reported neck pain was similar between groups (P = 0.39). Conclusions: Among community-dwelling elderly men, DISH prevalence is high, increases with age, and is positively associated with BMI and blood pressure. Frequency of self-reported back pain over the past 12 months was lower in older men with DISH as compared to those without DISH.
KW - Back pain
KW - Diffuse idiopathic skeletal hyperostosis
KW - Male
KW - Neck pain
UR - https://www.scopus.com/pages/publications/80755175885
UR - https://www.scopus.com/pages/publications/80755175885#tab=citedBy
U2 - 10.1016/j.semarthrit.2011.01.001
DO - 10.1016/j.semarthrit.2011.01.001
M3 - Article
C2 - 21377195
AN - SCOPUS:80755175885
SN - 0049-0172
VL - 41
SP - 131
EP - 138
JO - Seminars in Arthritis and Rheumatism
JF - Seminars in Arthritis and Rheumatism
IS - 2
ER -