TY - JOUR
T1 - Dipyridamole stress ultrasonic myocardial tissue characterization in patients with Kawasaki disease
AU - Yu, Xianyi
AU - Hashimoto, Ikuo
AU - Ichida, Fukiko
AU - Hamamichi, Yuji
AU - Uese, Kei Ichiro
AU - Tsubata, Shinichi
AU - Miyawaki, Toshio
AU - Seto, Hikaru
AU - Sahn, David J.
N1 - Funding Information:
Xianyi Yu, MD, is supported by grants from Ministry of Education of China.
PY - 2001/7
Y1 - 2001/7
N2 - Dipyridamole stress integrated backscatter (IBS) was used for evaluation of myocardial ischemia or damage in 31 children with coronary artery lesions caused by Kawasaki disease, in comparison with thallium-201 myocardial imaging. All patients underwent echocardiography at rest and after dipyridamole stress at the anterior interventricular septum, posterior wall (PW), and inferior wall (INF). At rest, no significant difference was seen in cyclic variation (CV) of IBS in the regions with normal or abnormal distribution on TI-201 imaging. But in the regions showing abnormal distribution after stress, CV decreased significantly. A delayed study after stress showed the recovery of CV to the level at rest in all patients. Sensitivity of abnormal cyclic variation integrated backscatter was 75% in the PW and 91% in the INF, and specificity was 91% in the PW and 90% in the INF, compared with the results of thallium-201 imaging. Dipyridamole stress IBS can provide sensitive detection of myocardial ischemia or damage in Kawasaki disease.
AB - Dipyridamole stress integrated backscatter (IBS) was used for evaluation of myocardial ischemia or damage in 31 children with coronary artery lesions caused by Kawasaki disease, in comparison with thallium-201 myocardial imaging. All patients underwent echocardiography at rest and after dipyridamole stress at the anterior interventricular septum, posterior wall (PW), and inferior wall (INF). At rest, no significant difference was seen in cyclic variation (CV) of IBS in the regions with normal or abnormal distribution on TI-201 imaging. But in the regions showing abnormal distribution after stress, CV decreased significantly. A delayed study after stress showed the recovery of CV to the level at rest in all patients. Sensitivity of abnormal cyclic variation integrated backscatter was 75% in the PW and 91% in the INF, and specificity was 91% in the PW and 90% in the INF, compared with the results of thallium-201 imaging. Dipyridamole stress IBS can provide sensitive detection of myocardial ischemia or damage in Kawasaki disease.
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U2 - 10.1067/mje.2001.111532
DO - 10.1067/mje.2001.111532
M3 - Article
C2 - 11447413
AN - SCOPUS:0035182343
SN - 0894-7317
VL - 14
SP - 682
EP - 690
JO - Journal of the American Society of Echocardiography
JF - Journal of the American Society of Echocardiography
IS - 7
ER -