Dipyridamole stress ultrasonic myocardial tissue characterization in patients with Kawasaki disease

Xianyi Yu, Ikuo Hashimoto, Fukiko Ichida, Yuji Hamamichi, Kei Ichiro Uese, Shinichi Tsubata, Toshio Miyawaki, Hikaru Seto, David J. Sahn

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Dipyridamole stress integrated backscatter (IBS) was used for evaluation of myocardial ischemia or damage in 31 children with coronary artery lesions caused by Kawasaki disease, in comparison with thallium-201 myocardial imaging. All patients underwent echocardiography at rest and after dipyridamole stress at the anterior interventricular septum, posterior wall (PW), and inferior wall (INF). At rest, no significant difference was seen in cyclic variation (CV) of IBS in the regions with normal or abnormal distribution on TI-201 imaging. But in the regions showing abnormal distribution after stress, CV decreased significantly. A delayed study after stress showed the recovery of CV to the level at rest in all patients. Sensitivity of abnormal cyclic variation integrated backscatter was 75% in the PW and 91% in the INF, and specificity was 91% in the PW and 90% in the INF, compared with the results of thallium-201 imaging. Dipyridamole stress IBS can provide sensitive detection of myocardial ischemia or damage in Kawasaki disease.

Original languageEnglish (US)
Pages (from-to)682-690
Number of pages9
JournalJournal of the American Society of Echocardiography
Issue number7
StatePublished - Jul 2001
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Dipyridamole stress ultrasonic myocardial tissue characterization in patients with Kawasaki disease'. Together they form a unique fingerprint.

Cite this