Abstract
Epidermal growth factor and nerve growth factor (NGF) lead to significantly different temporal patterns of extracellular-signal-regulated kinase activation, and differential regulation of Ras and Rap1 have been implicated in mediating this temporal specificity. Now Sasagawa et al. derive a computational model that incorporates the known signalling interactions and identifies key points of regulation that control these processes.
Original language | English (US) |
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Pages (from-to) | 338-339 |
Number of pages | 2 |
Journal | Nature Cell Biology |
Volume | 7 |
Issue number | 4 |
DOIs | |
State | Published - Apr 2005 |
ASJC Scopus subject areas
- Cell Biology