Disseminated nocardiosis with infective endocarditis of a transplanted heart

Antonious Ziad Hazim, André Martin Mansoor

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Nocardiosis is caused by various species of Nocardia and typically occurs as an opportunistic infection. It frequently disseminates, most often involving the lungs, subcutaneous tissues and central nervous system. It has rarely been reported to affect native heart valves. We report the case of a 64-year-old man with disseminated nocardiosis involving the brain, lungs, muscle and tricuspid valve of a transplanted heart. Following antimicrobial therapy, the patient improved clinically and there was no evidence of residual infection on follow-up imaging. This case highlights the presentation of nocardiosis, current therapeutic guidelines and the question of prophylaxis against Nocardia in immunocompromised patients.

Original languageEnglish (US)
Article number225046
JournalBMJ Case Reports
StatePublished - 2018


  • TB and other respiratory ionfections
  • immunology
  • infection (neurology)
  • transplantation
  • valvar diseases

ASJC Scopus subject areas

  • Medicine(all)


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