Divalent Cation Requirements for Leukocyte Adhesiveness

Richard E. Bryant

doi:10.3181/00379727-130-33701

Divalent Cation Requirements for Leukocyte Adhesiveness

Richard E. Bryant

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Using a chelating agent which binds calcium ions 100,000-fold more avidly than magnesium ions (EGTA) it was demonstrated that PMN adhesion to glass or to other leukocytes was not a calcium-dependent process and that a slight excess of magnesium ion actually caused increased PMN adhesiveness in the virtual absence of calcium.

Original language	English (US)
Pages (from-to)	975-977
Number of pages	3
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	130
Issue number	3
DOIs	https://doi.org/10.3181/00379727-130-33701
State	Published - Mar 1969
Externally published	Yes

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.3181/00379727-130-33701

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title = "Divalent Cation Requirements for Leukocyte Adhesiveness",

abstract = "Using a chelating agent which binds calcium ions 100,000-fold more avidly than magnesium ions (EGTA) it was demonstrated that PMN adhesion to glass or to other leukocytes was not a calcium-dependent process and that a slight excess of magnesium ion actually caused increased PMN adhesiveness in the virtual absence of calcium.",

author = "Bryant, {Richard E.}",

note = "Funding Information: Supported in part by Research Grants HE 08399 and AI 00323 from the U. S. Public Health Service, National Institutes of Health, Bethesda, Maryland. 1 ",

year = "1969",

month = mar,

doi = "10.3181/00379727-130-33701",

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PY - 1969/3

Y1 - 1969/3

N2 - Using a chelating agent which binds calcium ions 100,000-fold more avidly than magnesium ions (EGTA) it was demonstrated that PMN adhesion to glass or to other leukocytes was not a calcium-dependent process and that a slight excess of magnesium ion actually caused increased PMN adhesiveness in the virtual absence of calcium.

AB - Using a chelating agent which binds calcium ions 100,000-fold more avidly than magnesium ions (EGTA) it was demonstrated that PMN adhesion to glass or to other leukocytes was not a calcium-dependent process and that a slight excess of magnesium ion actually caused increased PMN adhesiveness in the virtual absence of calcium.

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JO - Proceedings of the Society for Experimental Biology and Medicine

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Divalent Cation Requirements for Leukocyte Adhesiveness

Abstract

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