DNA methylation analysis in human cancer

Eileen O'Sullivan, Michael Goggins

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Scopus citations


The functional impact of aberrant DNA methylation and the widespread alterations in DNA methylation in cancer development have led to the development of a variety of methods to characterize the DNA methylation patterns. This chapter critiques and describes the major approaches to analyzing DNA methylation.

Original languageEnglish (US)
Title of host publicationPancreatic Cancer
Subtitle of host publicationMethods and Protocols
PublisherHumana Press Inc.
Number of pages26
ISBN (Print)9781627032865
StatePublished - 2013
Externally publishedYes

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745


  • 5-Aza-deoxycytidine
  • 5-Hydroxymethylcytosine
  • 5-Methylcytosine
  • Bisulfite
  • CpG island
  • Methylation-specific PCR
  • Methylbinding protein

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics


Dive into the research topics of 'DNA methylation analysis in human cancer'. Together they form a unique fingerprint.

Cite this