DOTAM Derivatives as Active Cartilage-Targeting Drug Carriers for the Treatment of Osteoarthritis

Engineering & Materials Science

• Drug Delivery Systems 100%
• Cathepsins 96%
• Peptides 89%
• Cartilage 89%
• Peptide Hydrolases 68%
• Derivatives 55%
• Targeted drug delivery 38%
• Fluorophores 37%
• Amides 34%
• Collagen 30%
• Model structures 23%
• Acids 20%
• Degradation 15%

Medicine & Life Sciences

• Drug Carriers 81%
• Osteoarthritis 60%
• Cartilage 59%
• Cathepsin D 44%
• Peptides 32%
• 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid 28%
• Pharmaceutical Preparations 28%
• pepstatin 25%
• Amides 20%
• Protease Inhibitors 17%
• Knee Joint 17%
• Peptide Hydrolases 14%
• Collagen 12%
• Therapeutics 11%
• Injections 9%

Chemical Compounds

• Drug Carrier 72%
• Peptide 39%
• Drug 35%
• Pepstatin 33%
• 1,4,7,10-tetraazacyclododecane 31%
• Acid Amide 28%
• Protease Inhibitor 26%
• Collagen 21%
• Probe 13%