Effect of EDTA on the solid phase clq immune complex assay

Michael P. Davey, Leonhard Korngold

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


A solid-phase Clq immune complex (IC) assay (C1q-SP) is described. Wells of microtiter plates are coated with Clq, sera diluted 1:40 are added, and complexed IgG bound to the solid phase is detected by peroxidase-labeled protein A. This assay selectively binds aggregated human gammaglobulin and soluble IC prepared in vitro. Treatment of sera with EDTA prior to Clq-SP analysis interferes with the test.

Original languageEnglish (US)
Pages (from-to)275-277
Number of pages3
JournalInternational Archives of Allergy and Immunology
Issue number3
StatePublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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