Effect of melatonin on intraocular pressure

John R. Samples, Gregory Krause, Alfred J. Lewy

Research output: Contribution to journalArticlepeer-review

78 Scopus citations


We studied the effect of orally administered melatonin on intraocular pressure in humans. We suppressed serum melatonin levels by exposing our subjects to bright light. Our experiments suggest that melatonin lowers intraocular pressure in man. This may prove to be a therapeutically useful agent since melatonin appears to be relatively free of side effects and is effective in small quantities.

Original languageEnglish (US)
Pages (from-to)649-653
Number of pages5
JournalCurrent Eye Research
Issue number7
StatePublished - 1988

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience


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