Effect of novel bioactive glass-containing dentin adhesive on the permeability of demineralized dentin

Hyun Jung Kim, Ji Hyun Jang, Sang Uk Woo, Kyoung Kyu Choi, Sun Young Kim, Jack L. Ferracane, Jung Hwan Lee, Dongseok Choi, Samjin Choi, Soogeun Kim, Ayoung Bang, Duck Su Kim

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


This study aimed to evaluate the effect of a novel bioactive glass (BAG)-containing dentin adhesive on the permeability of demineralized dentin. Bioactive glass (85% SiO2, 15% CaO) was fabricated using the sol-gel process, and two experimental dentin adhesives were prepared with 3 wt% silica (silica-containing dentin adhesive; SCA) or BAG (BAG-containing dentin adhesive; BCA). Micro-tensile bond strength (µTBS) test, fracture mode analysis, field-emission scanning electron microscopy (FE-SEM) analysis of adhesive and demineralized dentin, real-time dentinal fluid flow (DFF) rate measurement, and Raman confocal microscopy were performed to compare SCA and BCA. There was no difference in µTBS between the SCA and BCA (p > 0.05). Multiple precipitates were evident on the surface of the BCA, and partial occlusion of dentinal tubules was observed in FE-SEM of BCA-approximated dentin. The DFF rate was reduced by 50.10% after BCA approximation and increased by 6.54% after SCA approximation. Raman confocal spectroscopy revealed an increased intensity of the hydroxyapatite (HA) peak on the dentin surface after BCA application. The novel BAG-containing dentin adhesive showed the potential of both reducing dentin permeability and dentin remineralization.

Original languageEnglish (US)
Article number5423
Issue number18
StatePublished - Sep 2021


  • Bioactive glass
  • Dentin permeability
  • Dentin remineralization
  • Dentinal fluid flow
  • Field-emission scanning electron microscopy
  • Raman confocal spectroscopy

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics


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