Effect of pregnancy on the pharmacokinetics of paclitaxel: A case report

Jennifer L. Lycette, Carrie L. Dul, Myrna Munar, Donna Belle, Stephen Y. Chui, Dennis R. Koop, Craig R. Nichols

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


Breast cancer during pregnancy is increasingly common as women delay childbearing until later in life. Safe administration of adjuvant chemotherapy during pregnancy has been reported. Physiologic and metabolic changes during pregnancy could alter the pharmacokinetics of these agents. This is a pilot study to prospectively study the pharmacokinetics of chemotherapeutic agents during pregnancy. Herein, we report the initial results with paclitaxel in the first patient.

Original languageEnglish (US)
Pages (from-to)342-344
Number of pages3
JournalClinical Breast Cancer
Issue number4
StatePublished - Oct 2006


  • Chemotherapy
  • Dose-dense therapy
  • Taxanes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


Dive into the research topics of 'Effect of pregnancy on the pharmacokinetics of paclitaxel: A case report'. Together they form a unique fingerprint.

Cite this