Effects of Pentoxifylline on Experimental Skin Flap Survival

Richard S. Hodgson, Robert E. Brummett, Ted A. Cook

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


We studied the effects of pentoxifylline on experimental skin flap survival in the domestic pig. Random skin flaps were designed using a length-width ratio of 5:1. The pigs were then given pentoxifylline (25 mg/kg/d) or placebo for seven days. Fluorescein sodium was used to help determine surviving skin flap length seven days postoperatively. Results showed no significant difference in mean surviving skin flap length between the study and control groups. We question the value of pentoxifylline in increasing skin flap survival.

Original languageEnglish (US)
Pages (from-to)950-952
Number of pages3
JournalArchives of Otolaryngology--Head and Neck Surgery
Issue number9
StatePublished - Sep 1987

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology


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