Effects of Positive End‐Expiratory Pressure on Renal Function

P. ‐O Järnberg; E. Dominguez de Villota; J. Eklund; P. ‐O Granberg

doi:10.1111/j.1399-6576.1978.tb01331.x

Effects of Positive End‐Expiratory Pressure on Renal Function

P. ‐O Järnberg
, E. Dominguez de Villota
, J. Eklund
, P. ‐O Granberg

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

The effects were studied of positive end‐expiratory pressure (PEEP) on renal function in eight patients with acute respiratory failure, requiring mechanical ventilation. On application of PEEP+ 10 cmH₂O, central venous pressure increased, systolic blood pressure decreased, urine flow and PAH‐clearance were reduced, while inulin clearance remained stable. There was a marked increase in fractional sodium reabsorption and a concurrent decrease in fractional osmolal excretion. Fractional free‐water clearance and the ratio Uo_sm/Po_sm did not change.

Original language	English (US)
Pages (from-to)	508-514
Number of pages	7
Journal	Acta Anaesthesiologica Scandinavica
Volume	22
Issue number	5
DOIs	https://doi.org/10.1111/j.1399-6576.1978.tb01331.x
State	Published - Oct 1978
Externally published	Yes

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

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Effects of Positive End‐Expiratory Pressure on Renal Function

Abstract

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