Efficacy and Toxicity of Classical Immunosuppressants, Retinoids and Biologics in Hidradenitis Suppurativa

Kinnor Das; Steven Daveluy; George Kroumpouzos; Komal Agarwal; Indrashis Podder; Katherine Farnbach; Alex G. Ortega-Loayza; Jacek C. Szepietowski; Stephan Grabbe; Mohamad Goldust

doi:10.3390/jcm11030670

Efficacy and Toxicity of Classical Immunosuppressants, Retinoids and Biologics in Hidradenitis Suppurativa

Kinnor Das, Steven Daveluy, George Kroumpouzos, Komal Agarwal, Indrashis Podder, Katherine Farnbach, Alex G. Ortega-Loayza, Jacek C. Szepietowski, Stephan Grabbe, Mohamad Goldust

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of the apocrine glands characterized by recurrent episodes. Although several therapies exist, none is completely curative. Several immunosuppressives have been studied with encouraging results and targeted approaches. In this review, we highlight the various immunosuppressives used in this condition along with their salient features to enable physicians to choose the correct therapy for their patients. The search of the peer-reviewed literature included clinical trials, scientific reviews, case series, case reports, and guidelines. The literature was identified from electronic databases (MEDLINE and PubMed) through November 2021; additional articles were included from the references of the identified ar-ticles.

Original language	English (US)
Article number	670
Journal	Journal of Clinical Medicine
Volume	11
Issue number	3
DOIs	https://doi.org/10.3390/jcm11030670
State	Published - Feb 1 2022

Keywords

Hidradenitis suppurativa
Immunosuppressants
Treatment

ASJC Scopus subject areas

General Medicine

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10.3390/jcm11030670

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title = "Efficacy and Toxicity of Classical Immunosuppressants, Retinoids and Biologics in Hidradenitis Suppurativa",

abstract = "Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of the apocrine glands characterized by recurrent episodes. Although several therapies exist, none is completely curative. Several immunosuppressives have been studied with encouraging results and targeted approaches. In this review, we highlight the various immunosuppressives used in this condition along with their salient features to enable physicians to choose the correct therapy for their patients. The search of the peer-reviewed literature included clinical trials, scientific reviews, case series, case reports, and guidelines. The literature was identified from electronic databases (MEDLINE and PubMed) through November 2021; additional articles were included from the references of the identified ar-ticles.",

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AU - Daveluy, Steven

AU - Kroumpouzos, George

AU - Agarwal, Komal

AU - Podder, Indrashis

AU - Farnbach, Katherine

AU - Ortega-Loayza, Alex G.

AU - Szepietowski, Jacek C.

AU - Grabbe, Stephan

AU - Goldust, Mohamad

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N2 - Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of the apocrine glands characterized by recurrent episodes. Although several therapies exist, none is completely curative. Several immunosuppressives have been studied with encouraging results and targeted approaches. In this review, we highlight the various immunosuppressives used in this condition along with their salient features to enable physicians to choose the correct therapy for their patients. The search of the peer-reviewed literature included clinical trials, scientific reviews, case series, case reports, and guidelines. The literature was identified from electronic databases (MEDLINE and PubMed) through November 2021; additional articles were included from the references of the identified ar-ticles.

AB - Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of the apocrine glands characterized by recurrent episodes. Although several therapies exist, none is completely curative. Several immunosuppressives have been studied with encouraging results and targeted approaches. In this review, we highlight the various immunosuppressives used in this condition along with their salient features to enable physicians to choose the correct therapy for their patients. The search of the peer-reviewed literature included clinical trials, scientific reviews, case series, case reports, and guidelines. The literature was identified from electronic databases (MEDLINE and PubMed) through November 2021; additional articles were included from the references of the identified ar-ticles.

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Efficacy and Toxicity of Classical Immunosuppressants, Retinoids and Biologics in Hidradenitis Suppurativa

Abstract

Keywords

ASJC Scopus subject areas

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