TY - JOUR
T1 - Efficacy and Toxicity of Classical Immunosuppressants, Retinoids and Biologics in Hidradenitis Suppurativa
AU - Das, Kinnor
AU - Daveluy, Steven
AU - Kroumpouzos, George
AU - Agarwal, Komal
AU - Podder, Indrashis
AU - Farnbach, Katherine
AU - Ortega-Loayza, Alex G.
AU - Szepietowski, Jacek C.
AU - Grabbe, Stephan
AU - Goldust, Mohamad
N1 - Funding Information:
Funding: The study was founded with the Research Grant from Wrocław Medical University (number: SUB.C260.22.056).
Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/2/1
Y1 - 2022/2/1
N2 - Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of the apocrine glands characterized by recurrent episodes. Although several therapies exist, none is completely curative. Several immunosuppressives have been studied with encouraging results and targeted approaches. In this review, we highlight the various immunosuppressives used in this condition along with their salient features to enable physicians to choose the correct therapy for their patients. The search of the peer-reviewed literature included clinical trials, scientific reviews, case series, case reports, and guidelines. The literature was identified from electronic databases (MEDLINE and PubMed) through November 2021; additional articles were included from the references of the identified ar-ticles.
AB - Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of the apocrine glands characterized by recurrent episodes. Although several therapies exist, none is completely curative. Several immunosuppressives have been studied with encouraging results and targeted approaches. In this review, we highlight the various immunosuppressives used in this condition along with their salient features to enable physicians to choose the correct therapy for their patients. The search of the peer-reviewed literature included clinical trials, scientific reviews, case series, case reports, and guidelines. The literature was identified from electronic databases (MEDLINE and PubMed) through November 2021; additional articles were included from the references of the identified ar-ticles.
KW - Hidradenitis suppurativa
KW - Immunosuppressants
KW - Treatment
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U2 - 10.3390/jcm11030670
DO - 10.3390/jcm11030670
M3 - Review article
AN - SCOPUS:85123378276
SN - 2077-0383
VL - 11
JO - Journal of Clinical Medicine
JF - Journal of Clinical Medicine
IS - 3
M1 - 670
ER -