Electron microscopy and HLA expression of a new cell line of retinoblastoma

G. A. Fournier; D. N. Sang; D. M. Albert; J. L. Craft

Electron microscopy and HLA expression of a new cell line of retinoblastoma

G. A. Fournier, D. N. Sang, D. M. Albert, J. L. Craft

Research output: Contribution to journal › Article › peer-review

Abstract

A new continuous retinoblastoma cell line (Rb 355-7) derived from a nonfamilial unilaterally-affected child was studied morphologically and with regard to HLA expression. The tumor was compared with two older and widely studied cell lines, the Y-79 and WERI-Rb1 strains. The Rb 355-7 line grew in tissue culture in clusters and chains. Its doubling time was calculated to be 4.4 days. In contrast to the Y-79 and WERI-Rb1 cell lines, the Rb355-7 showed a paucity of HLA expression.

Original language	English (US)
Pages (from-to)	690-699
Number of pages	10
Journal	Investigative Ophthalmology and Visual Science
Volume	28
Issue number	4
State	Published - 1987
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology
Sensory Systems
Cellular and Molecular Neuroscience

Cite this

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title = "Electron microscopy and HLA expression of a new cell line of retinoblastoma",

abstract = "A new continuous retinoblastoma cell line (Rb 355-7) derived from a nonfamilial unilaterally-affected child was studied morphologically and with regard to HLA expression. The tumor was compared with two older and widely studied cell lines, the Y-79 and WERI-Rb1 strains. The Rb 355-7 line grew in tissue culture in clusters and chains. Its doubling time was calculated to be 4.4 days. In contrast to the Y-79 and WERI-Rb1 cell lines, the Rb355-7 showed a paucity of HLA expression.",

author = "Fournier, {G. A.} and Sang, {D. N.} and Albert, {D. M.} and Craft, {J. L.}",

year = "1987",

language = "English (US)",

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T1 - Electron microscopy and HLA expression of a new cell line of retinoblastoma

AU - Fournier, G. A.

AU - Sang, D. N.

AU - Albert, D. M.

AU - Craft, J. L.

PY - 1987

Y1 - 1987

N2 - A new continuous retinoblastoma cell line (Rb 355-7) derived from a nonfamilial unilaterally-affected child was studied morphologically and with regard to HLA expression. The tumor was compared with two older and widely studied cell lines, the Y-79 and WERI-Rb1 strains. The Rb 355-7 line grew in tissue culture in clusters and chains. Its doubling time was calculated to be 4.4 days. In contrast to the Y-79 and WERI-Rb1 cell lines, the Rb355-7 showed a paucity of HLA expression.

AB - A new continuous retinoblastoma cell line (Rb 355-7) derived from a nonfamilial unilaterally-affected child was studied morphologically and with regard to HLA expression. The tumor was compared with two older and widely studied cell lines, the Y-79 and WERI-Rb1 strains. The Rb 355-7 line grew in tissue culture in clusters and chains. Its doubling time was calculated to be 4.4 days. In contrast to the Y-79 and WERI-Rb1 cell lines, the Rb355-7 showed a paucity of HLA expression.

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C2 - 3549617

AN - SCOPUS:0023091597

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JF - Investigative Ophthalmology and Visual Science

IS - 4

ER -

Electron microscopy and HLA expression of a new cell line of retinoblastoma

Abstract

ASJC Scopus subject areas

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