Electroshock effects on brain protein synthesis: Relation to brain seizures and retrograde amnesia

Carl W. Cotman; Gary Banker; Steven F. Zornetzer; James L. Mcgaugh

doi:10.1126/science.173.3995.454

Electroshock effects on brain protein synthesis: Relation to brain seizures and retrograde amnesia

Carl W. Cotman, Gary Banker, Steven F. Zornetzer, James L. Mcgaugh

Research output: Contribution to journal › Article › peer-review

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Abstract

The effects of electroshock on brain seizure activity and brain protein synthesis were studied in male mice. A significant but short-lasting inhibition of brain protein synthesis and an increase in the amount of free leucine were produced by electroshock at intensities above the brain seizure threshold. Electroshock at intensities below the brain seizure threshold did not affect brain protein synthesis.

Original language	English (US)
Pages (from-to)	454-456
Number of pages	3
Journal	Science
Volume	173
Issue number	3995
DOIs	https://doi.org/10.1126/science.173.3995.454
State	Published - 1971
Externally published	Yes

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title = "Electroshock effects on brain protein synthesis: Relation to brain seizures and retrograde amnesia",

abstract = "The effects of electroshock on brain seizure activity and brain protein synthesis were studied in male mice. A significant but short-lasting inhibition of brain protein synthesis and an increase in the amount of free leucine were produced by electroshock at intensities above the brain seizure threshold. Electroshock at intensities below the brain seizure threshold did not affect brain protein synthesis.",

author = "Cotman, {Carl W.} and Gary Banker and Zornetzer, {Steven F.} and Mcgaugh, {James L.}",

year = "1971",

doi = "10.1126/science.173.3995.454",

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AU - Cotman, Carl W.

AU - Banker, Gary

AU - Zornetzer, Steven F.

AU - Mcgaugh, James L.

PY - 1971

Y1 - 1971

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AB - The effects of electroshock on brain seizure activity and brain protein synthesis were studied in male mice. A significant but short-lasting inhibition of brain protein synthesis and an increase in the amount of free leucine were produced by electroshock at intensities above the brain seizure threshold. Electroshock at intensities below the brain seizure threshold did not affect brain protein synthesis.

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Electroshock effects on brain protein synthesis: Relation to brain seizures and retrograde amnesia

Abstract

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