Emerging diagnostic challenges and characteristics of simian betaretrovirus infections in captive macaque colonies

Jo Ann L. Yee; Richard Grant; Koen K. Van Rompay; La Rene Kuller; Amanda Carpenter; Robin Watanabe; Rebeca Huebner; Brian Agricola; Jeremy Smedley; Jeffrey A. Roberts

doi:10.1111/jmp.12295

Emerging diagnostic challenges and characteristics of simian betaretrovirus infections in captive macaque colonies

Jo Ann L. Yee, Richard Grant, Koen K. Van Rompay, La Rene Kuller, Amanda Carpenter, Robin Watanabe, Rebeca Huebner, Brian Agricola, Jeremy Smedley, Jeffrey A. Roberts

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

To better understand Simian betaretrovirus (SRV) seropositivity in virus-negative macaques, we transfused blood from SRV-infected or suspect donors into immunosuppressed naive recipients. Our results do not support typical SRV1-5 infection as the cause, but provide evidence for several possibilities including serological artifact, new/different SRV, or an endogenous virus.

Original language	English (US)
Pages (from-to)	149-153
Number of pages	5
Journal	Journal of medical primatology
Volume	46
Issue number	4
DOIs	https://doi.org/10.1111/jmp.12295
State	Published - Aug 2017
Externally published	Yes

Keywords

PCR
endogenous virus
serology
transfusion

ASJC Scopus subject areas

Animal Science and Zoology
General Veterinary

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10.1111/jmp.12295

Cite this

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title = "Emerging diagnostic challenges and characteristics of simian betaretrovirus infections in captive macaque colonies",

abstract = "To better understand Simian betaretrovirus (SRV) seropositivity in virus-negative macaques, we transfused blood from SRV-infected or suspect donors into immunosuppressed naive recipients. Our results do not support typical SRV1-5 infection as the cause, but provide evidence for several possibilities including serological artifact, new/different SRV, or an endogenous virus.",

keywords = "PCR, endogenous virus, serology, transfusion",

author = "Yee, {Jo Ann L.} and Richard Grant and {Van Rompay}, {Koen K.} and Kuller, {La Rene} and Amanda Carpenter and Robin Watanabe and Rebeca Huebner and Brian Agricola and Jeremy Smedley and Roberts, {Jeffrey A.}",

note = "Publisher Copyright: {\textcopyright} 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd",

year = "2017",

month = aug,

doi = "10.1111/jmp.12295",

language = "English (US)",

volume = "46",

pages = "149--153",

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AU - Yee, Jo Ann L.

AU - Grant, Richard

AU - Van Rompay, Koen K.

AU - Kuller, La Rene

AU - Carpenter, Amanda

AU - Watanabe, Robin

AU - Huebner, Rebeca

AU - Agricola, Brian

AU - Smedley, Jeremy

AU - Roberts, Jeffrey A.

PY - 2017/8

Y1 - 2017/8

N2 - To better understand Simian betaretrovirus (SRV) seropositivity in virus-negative macaques, we transfused blood from SRV-infected or suspect donors into immunosuppressed naive recipients. Our results do not support typical SRV1-5 infection as the cause, but provide evidence for several possibilities including serological artifact, new/different SRV, or an endogenous virus.

AB - To better understand Simian betaretrovirus (SRV) seropositivity in virus-negative macaques, we transfused blood from SRV-infected or suspect donors into immunosuppressed naive recipients. Our results do not support typical SRV1-5 infection as the cause, but provide evidence for several possibilities including serological artifact, new/different SRV, or an endogenous virus.

KW - PCR

KW - endogenous virus

KW - serology

KW - transfusion

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JF - Journal of medical primatology

IS - 4

ER -

Emerging diagnostic challenges and characteristics of simian betaretrovirus infections in captive macaque colonies

Abstract

Keywords

ASJC Scopus subject areas

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