Estrogen stimulation of progesterone synthesis by porcine granulosa cells in culture

Robert L. Goldenberg; William E. Bridson; Peter O. Kohler

doi:10.1016/0006-291X(72)90349-X

Estrogen stimulation of progesterone synthesis by porcine granulosa cells in culture

Robert L. Goldenberg, William E. Bridson, Peter O. Kohler

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

Estrogen stimulates synthesis of progesterone by porcine granulosa cells in tissue culture. This enhancement is inhibited by cycloheximide, suggesting that protein synthesis is required for the effect. Estrogen is synergistic with hCG in increasing progesterone synthesis. Sequential treatment with hCG followed by estradiol causes maximal stimulation of progesterone production.

Original language	English (US)
Pages (from-to)	101-107
Number of pages	7
Journal	Biochemical and Biophysical Research Communications
Volume	48
Issue number	1
DOIs	https://doi.org/10.1016/0006-291X(72)90349-X
State	Published - Jul 11 1972
Externally published	Yes

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

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10.1016/0006-291X(72)90349-X

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title = "Estrogen stimulation of progesterone synthesis by porcine granulosa cells in culture",

abstract = "Estrogen stimulates synthesis of progesterone by porcine granulosa cells in tissue culture. This enhancement is inhibited by cycloheximide, suggesting that protein synthesis is required for the effect. Estrogen is synergistic with hCG in increasing progesterone synthesis. Sequential treatment with hCG followed by estradiol causes maximal stimulation of progesterone production.",

author = "Goldenberg, {Robert L.} and Bridson, {William E.} and Kohler, {Peter O.}",

year = "1972",

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AU - Bridson, William E.

AU - Kohler, Peter O.

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AB - Estrogen stimulates synthesis of progesterone by porcine granulosa cells in tissue culture. This enhancement is inhibited by cycloheximide, suggesting that protein synthesis is required for the effect. Estrogen is synergistic with hCG in increasing progesterone synthesis. Sequential treatment with hCG followed by estradiol causes maximal stimulation of progesterone production.

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Estrogen stimulation of progesterone synthesis by porcine granulosa cells in culture

Abstract

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