@article{0d6d8998f5104bb79a969a9b4b3044bd,
title = "Expression of chimeric antigen receptor therapy targets detected by single-cell sequencing of normal cells may contribute to off-tumor toxicity",
author = "Ying Jing and Yuan Liu and Qiang Li and Youqiong Ye and Lixia Diao and Yun Huang and Yubin Zhou and Green, \{Michael R.\} and Mills, \{Gordon B.\} and Leng Han",
note = "Funding Information: This work was supported by the Cancer Prevention \& Research Institute of Texas ( RR150085 and RP190570 to L.H.), NIH ( U01 CA217842 to G.B.M), and The Welch Foundation ( BE-1913-20190330 to Y.Z.). M.R.G is a Scholar of the Leukemia and Lymphoma Society. We thank LeeAnn Chastain for editorial assistance. Detailed methods and list of CAR targets are available at https://hanlab.tamhsc.edu/CARTSC/\#!/download , and all other associated data are available within the data portal. Funding Information: This work was supported by the Cancer Prevention \& Research Institute of Texas (RR150085 and RP190570 to L.H.), NIH (U01 CA217842 to G.B.M), and The Welch Foundation (BE-1913-20190330 to Y.Z.). M.R.G is a Scholar of the Leukemia and Lymphoma Society. We thank LeeAnn Chastain for editorial assistance. Detailed methods and list of CAR targets are available at https://hanlab.tamhsc.edu/CARTSC/\#!/download, and all other associated data are available within the data portal. M.R.G. has stock ownership interest in KDAc Therapeutics; receives funding from Kite/Gilead, Allogene, Sanofi, and Abbvie; and has received an honorarium from Tessa Therapeutics. G.B.M notes personal fees for consulting from Abbvie, Amphista, AstraZeneca, Chrysallis Biotechnology, GSK, ELlipses Pharma, ImmunoMET, Ionis, Lilly, Medacorp, PDX Pharmaceuticals, Signalchem Lifesciences, Symphogen, Tarveda, Turbine, and Zentalis Pharmaceuticals; stock options from Catena Pharmaceuticals, ImmunoMet, SignalChem, Tarveda, and Turbine; and has licensed technology of homologous recombination deficiency (HRD) assay to Myriad Genetics and digital saptial profiler (DSP ) patents with Nanostring. All other authors declare no competing interests.",
year = "2021",
month = dec,
day = "13",
doi = "10.1016/j.ccell.2021.09.016",
language = "English (US)",
volume = "39",
pages = "1558--1559",
journal = "Cancer Cell",
issn = "1535-6108",
publisher = "Cell Press",
number = "12",
}