Extraarticular Manifestations: Uveitis, Colitis, Psoriasis

Sonam Kiwalkar; James T. Rosenbaum; Sergio Schwartzman; Jan Peter Dutz; Filip Van Den Bosch

doi:10.1016/B978-0-323-56800-5.00011-4

Extraarticular Manifestations: Uveitis, Colitis, Psoriasis

Sonam Kiwalkar, James T. Rosenbaum, Sergio Schwartzman, Jan Peter Dutz, Filip Van Den Bosch

Ophthalmology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Extraarticular manifestations (EAMs) associated with axial spondyloarthritis (axSpA) include conditions involving the skin, eye, gastrointestinal, and cardiorespiratory systems. Epidemiologic studies report their prevalence to be higher in patients with axSpA, as compared with the general population: acute anterior uveitis in 10%-40%, inflammatory bowel disease in 5%-10%, and psoriasis in 5%-10% of axSpA patients. They have a major impact on the management of axSpA and require a multispecialty approach. Moreover, their presence increases the disease burden on patients and society. Better knowledge of critical pathogenic pathways of axSpA and its EAMs could pave the road for future therapeutic approaches.

Original language	English (US)
Title of host publication	Axial Spondyloarthritis
Publisher	Elsevier
Pages	157-182
Number of pages	26
ISBN (Electronic)	9780323568005
DOIs	https://doi.org/10.1016/B978-0-323-56800-5.00011-4
State	Published - Jan 1 2019

Keywords

Colitis
HLA-B27
Inflammatory bowel diseases
Psoriasis
Tumor necrosis factor inhibitors
Uveitis

ASJC Scopus subject areas

General Medicine

Access to Document

10.1016/B978-0-323-56800-5.00011-4

Cite this

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abstract = "Extraarticular manifestations (EAMs) associated with axial spondyloarthritis (axSpA) include conditions involving the skin, eye, gastrointestinal, and cardiorespiratory systems. Epidemiologic studies report their prevalence to be higher in patients with axSpA, as compared with the general population: acute anterior uveitis in 10%-40%, inflammatory bowel disease in 5%-10%, and psoriasis in 5%-10% of axSpA patients. They have a major impact on the management of axSpA and require a multispecialty approach. Moreover, their presence increases the disease burden on patients and society. Better knowledge of critical pathogenic pathways of axSpA and its EAMs could pave the road for future therapeutic approaches.",

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AU - Dutz, Jan Peter

AU - Van Den Bosch, Filip

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KW - HLA-B27

KW - Inflammatory bowel diseases

KW - Psoriasis

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Extraarticular Manifestations: Uveitis, Colitis, Psoriasis

Abstract

Keywords

ASJC Scopus subject areas

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