Feline uveal melanoma model induced with feline sarcoma virus

D. M. Albert, J. A. Shadduck, J. L. Craft, J. Y. Niederkorn

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


This paper describes the first animal model of a virally induced uveal melanoma. Tumors developed following the injection of an RNA tumor virus, i.e., Gardner strain feline sarcoma virus, into the anterior chamber of newborn kitterns. Histogically, the tumors were found to be iris and ciliary body melanomas, many of which showed invasion. The histology and ultrastructure of those tumors are described.

Original languageEnglish (US)
Pages (from-to)606-624
Number of pages19
JournalInvestigative Ophthalmology and Visual Science
Issue number5
StatePublished - 1981
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience


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