Femtosecond laser-assisted deep anterior lamellar keratoplasty

Research output: Contribution to journalReview articlepeer-review

24 Scopus citations


Purpose of reviewA survey of the recent literature of deep anterior lamellar keratoplasty using femtosecond laser technology.Recent findingsThere are several recent reports in the literature assessing technique and outcomes of deep anterior lamellar keratoplasty done with a femtosecond laser trephination. Most of these reports are laboratory studies and small case series with short-term outcomes. The laser technology is expensive and may not produce better results than conventional manual techniques. However, there are several theoretical advantages to femtosecond laser incisions in deep anterior lamellar keratoplasty that should be explored, including possible increased success of Descemet's membrane separation from stroma during surgery as well as postsurgical astigmatism benefits, earlier suture removal, and increased wound strength and healing.SummaryFemtosecond laser trephination in the setting of DALK may improve the technique by decreasing the number of descemet's membrane ruptures and improving short-term and long-term outcomes as compared with manual techniques. However, there is no consensus on a standardized approach for wound design or postoperative management. The literature would benefit from a prospective randomized controlled trial.

Original languageEnglish (US)
Pages (from-to)256-263
Number of pages8
JournalCurrent opinion in ophthalmology
Issue number4
StatePublished - Jul 1 2019


  • Descemet's membrane
  • big bubble
  • cost effectiveness analysis
  • deep anterior lamellar keratoplasty
  • endothelial cell density
  • femtosecond laser
  • femtosecond laser-assisted deep anterior lamellar keratoplasty
  • femtosecond laser-assisted penetrating keratoplasty
  • penetrating keratoplasty
  • wound strength

ASJC Scopus subject areas

  • Ophthalmology


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