TY - JOUR
T1 - Femtosecond laser-assisted deep anterior lamellar keratoplasty
AU - Chamberlain, Winston D.
N1 - Funding Information:
Supported by Grant P30 EY010572 from the National Institutes of Health (Bethesda, Maryland, USA), and by unrestricted departmental funding from Research to Prevent Blindness (New York city, New York, USA).
Publisher Copyright:
© 2019 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2019/7/1
Y1 - 2019/7/1
N2 - Purpose of reviewA survey of the recent literature of deep anterior lamellar keratoplasty using femtosecond laser technology.Recent findingsThere are several recent reports in the literature assessing technique and outcomes of deep anterior lamellar keratoplasty done with a femtosecond laser trephination. Most of these reports are laboratory studies and small case series with short-term outcomes. The laser technology is expensive and may not produce better results than conventional manual techniques. However, there are several theoretical advantages to femtosecond laser incisions in deep anterior lamellar keratoplasty that should be explored, including possible increased success of Descemet's membrane separation from stroma during surgery as well as postsurgical astigmatism benefits, earlier suture removal, and increased wound strength and healing.SummaryFemtosecond laser trephination in the setting of DALK may improve the technique by decreasing the number of descemet's membrane ruptures and improving short-term and long-term outcomes as compared with manual techniques. However, there is no consensus on a standardized approach for wound design or postoperative management. The literature would benefit from a prospective randomized controlled trial.
AB - Purpose of reviewA survey of the recent literature of deep anterior lamellar keratoplasty using femtosecond laser technology.Recent findingsThere are several recent reports in the literature assessing technique and outcomes of deep anterior lamellar keratoplasty done with a femtosecond laser trephination. Most of these reports are laboratory studies and small case series with short-term outcomes. The laser technology is expensive and may not produce better results than conventional manual techniques. However, there are several theoretical advantages to femtosecond laser incisions in deep anterior lamellar keratoplasty that should be explored, including possible increased success of Descemet's membrane separation from stroma during surgery as well as postsurgical astigmatism benefits, earlier suture removal, and increased wound strength and healing.SummaryFemtosecond laser trephination in the setting of DALK may improve the technique by decreasing the number of descemet's membrane ruptures and improving short-term and long-term outcomes as compared with manual techniques. However, there is no consensus on a standardized approach for wound design or postoperative management. The literature would benefit from a prospective randomized controlled trial.
KW - Descemet's membrane
KW - big bubble
KW - cost effectiveness analysis
KW - deep anterior lamellar keratoplasty
KW - endothelial cell density
KW - femtosecond laser
KW - femtosecond laser-assisted deep anterior lamellar keratoplasty
KW - femtosecond laser-assisted penetrating keratoplasty
KW - penetrating keratoplasty
KW - wound strength
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U2 - 10.1097/ICU.0000000000000574
DO - 10.1097/ICU.0000000000000574
M3 - Review article
C2 - 31033736
AN - SCOPUS:85067377131
SN - 1040-8738
VL - 30
SP - 256
EP - 263
JO - Current Opinion in Ophthalmology
JF - Current Opinion in Ophthalmology
IS - 4
ER -