Flash & Click: Multifunctionalized Lipid Derivatives as Tools to Study Viral Infections

Carsten Schultz; Scotland E. Farley; Fikadu G. Tafesse

doi:10.1021/jacs.2c02705

Flash & Click: Multifunctionalized Lipid Derivatives as Tools to Study Viral Infections

Carsten Schultz, Scotland E. Farley, Fikadu G. Tafesse

Molecular Microbiology and Immunology

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

In this perspective article, we describe the current status of lipid tools for studying host lipid-virus interactions at the cellular level. We discuss the potential lipidomic changes that viral infections impose on host cells and then outline the tools available and the resulting options to investigate the host cell lipid interactome. The future outcome will reveal new targets for treating virus infections.

Original language	English (US)
Pages (from-to)	13987-13995
Number of pages	9
Journal	Journal of the American Chemical Society
Volume	144
Issue number	31
DOIs	https://doi.org/10.1021/jacs.2c02705
State	Published - Aug 10 2022

ASJC Scopus subject areas

Catalysis
Chemistry(all)
Biochemistry
Colloid and Surface Chemistry

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10.1021/jacs.2c02705

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title = "Flash & Click: Multifunctionalized Lipid Derivatives as Tools to Study Viral Infections",

abstract = "In this perspective article, we describe the current status of lipid tools for studying host lipid-virus interactions at the cellular level. We discuss the potential lipidomic changes that viral infections impose on host cells and then outline the tools available and the resulting options to investigate the host cell lipid interactome. The future outcome will reveal new targets for treating virus infections.",

author = "Carsten Schultz and Farley, {Scotland E.} and Tafesse, {Fikadu G.}",

note = "Funding Information: Work relevant to this article is funded by the NIH (RO1AI141549 and R21 AI156174 to F.G. T., and R01GM127631 to C.S.). Publisher Copyright: {\textcopyright} 2022 American Chemical Society. All rights reserved.",

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T2 - Multifunctionalized Lipid Derivatives as Tools to Study Viral Infections

AU - Schultz, Carsten

AU - Farley, Scotland E.

AU - Tafesse, Fikadu G.

N1 - Funding Information: Work relevant to this article is funded by the NIH (RO1AI141549 and R21 AI156174 to F.G. T., and R01GM127631 to C.S.). Publisher Copyright: © 2022 American Chemical Society. All rights reserved.

PY - 2022/8/10

Y1 - 2022/8/10

N2 - In this perspective article, we describe the current status of lipid tools for studying host lipid-virus interactions at the cellular level. We discuss the potential lipidomic changes that viral infections impose on host cells and then outline the tools available and the resulting options to investigate the host cell lipid interactome. The future outcome will reveal new targets for treating virus infections.

AB - In this perspective article, we describe the current status of lipid tools for studying host lipid-virus interactions at the cellular level. We discuss the potential lipidomic changes that viral infections impose on host cells and then outline the tools available and the resulting options to investigate the host cell lipid interactome. The future outcome will reveal new targets for treating virus infections.

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JF - Journal of the American Chemical Society

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Flash & Click: Multifunctionalized Lipid Derivatives as Tools to Study Viral Infections

Abstract

ASJC Scopus subject areas

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