G-protein-coupled receptors: the new dopamine receptor subtypes

David K. Grandy; Olivier Civelli

doi:10.1016/0959-4388(92)90115-2

G-protein-coupled receptors: the new dopamine receptor subtypes

David K. Grandy, Olivier Civelli

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The family of genes encoding G-protein-coupled dopamine receptors continues to grow with the recent cloning of a fifth member. The availability of these clones has revolutionized the dopamine receptor field. Expression of individual dopamine receptors is permitting the detailed analysis of their pharmacology and coupling to second messenger systems, while probes based on the receptors' nucleotide sequences are being used to gain new insights into their tissue distribution and genetics.

Original language	English (US)
Pages (from-to)	275-281
Number of pages	7
Journal	Current Opinion in Neurobiology
Volume	2
Issue number	3
DOIs	https://doi.org/10.1016/0959-4388(92)90115-2
State	Published - Jun 1992
Externally published	Yes

ASJC Scopus subject areas

Neuroscience(all)

Access to Document

10.1016/0959-4388(92)90115-2

Cite this

@article{772de2cca94b40abb7223f7e039b127f,

title = "G-protein-coupled receptors: the new dopamine receptor subtypes",

abstract = "The family of genes encoding G-protein-coupled dopamine receptors continues to grow with the recent cloning of a fifth member. The availability of these clones has revolutionized the dopamine receptor field. Expression of individual dopamine receptors is permitting the detailed analysis of their pharmacology and coupling to second messenger systems, while probes based on the receptors' nucleotide sequences are being used to gain new insights into their tissue distribution and genetics.",

author = "Grandy, {David K.} and Olivier Civelli",

note = "Funding Information: We would like to thank our colleagues SJ Watson, J Meador-Woodruff, J Eubanks and J Gelemter for making unpublished results available to us. We would also Like to thank J Shiigl for preparing the illustration. The work presented from our laboratoty was supported in part by grants from the Supreme Council of the Scottish Rite (D Grandy, 0 Civelli) and National Institute of Health MH45614( 0 Civelli).",

year = "1992",

month = jun,

doi = "10.1016/0959-4388(92)90115-2",

language = "English (US)",

volume = "2",

pages = "275--281",

journal = "Current Opinion in Neurobiology",

issn = "0959-4388",

publisher = "Elsevier Limited",

number = "3",

}

TY - JOUR

T1 - G-protein-coupled receptors

T2 - the new dopamine receptor subtypes

AU - Grandy, David K.

AU - Civelli, Olivier

N1 - Funding Information: We would like to thank our colleagues SJ Watson, J Meador-Woodruff, J Eubanks and J Gelemter for making unpublished results available to us. We would also Like to thank J Shiigl for preparing the illustration. The work presented from our laboratoty was supported in part by grants from the Supreme Council of the Scottish Rite (D Grandy, 0 Civelli) and National Institute of Health MH45614( 0 Civelli).

PY - 1992/6

Y1 - 1992/6

N2 - The family of genes encoding G-protein-coupled dopamine receptors continues to grow with the recent cloning of a fifth member. The availability of these clones has revolutionized the dopamine receptor field. Expression of individual dopamine receptors is permitting the detailed analysis of their pharmacology and coupling to second messenger systems, while probes based on the receptors' nucleotide sequences are being used to gain new insights into their tissue distribution and genetics.

AB - The family of genes encoding G-protein-coupled dopamine receptors continues to grow with the recent cloning of a fifth member. The availability of these clones has revolutionized the dopamine receptor field. Expression of individual dopamine receptors is permitting the detailed analysis of their pharmacology and coupling to second messenger systems, while probes based on the receptors' nucleotide sequences are being used to gain new insights into their tissue distribution and genetics.

UR - http://www.scopus.com/inward/record.url?scp=0026877221&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026877221&partnerID=8YFLogxK

U2 - 10.1016/0959-4388(92)90115-2

DO - 10.1016/0959-4388(92)90115-2

M3 - Article

C2 - 1643409

AN - SCOPUS:0026877221

SN - 0959-4388

VL - 2

SP - 275

EP - 281

JO - Current Opinion in Neurobiology

JF - Current Opinion in Neurobiology

IS - 3

ER -

G-protein-coupled receptors: the new dopamine receptor subtypes

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this