Gallium-67 lung index computerization in interstitial pneumonitis

H. D. Specht, P. H. Brown, J. E. Haines, M. McNeill

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


To improve ease of use, precision, and reduce interobserver variability of the 67Ga lung index, we developed and tested a computer method that yields similar numeric values and uses previous indexing principles, except that the computer matrix unit is the fractional area assessed. Patients were referred for suspected interstitial lung disease. Fifty-three image studies were available for both manual and computer indexing. Linear regression analysis gave a correlation of 0.884. Decision matrix analysis of 58 different nonimmunosuppressed patients resulted in 93% sensitivity and 76% specificity. Receiver operating characteristic curve analysis showed that the ideal index cutoff was 50. Because there is tighter control over 67Ga uptake intensity and spatial distribution assessment, the computerized 67Ga index appears to perform better than the manual analysis.

Original languageEnglish (US)
Pages (from-to)1826-1830
Number of pages5
JournalJournal of Nuclear Medicine
Issue number12
StatePublished - 1987
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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