Gastrointestinal Complications of Ehlers-Danlos Syndrome

David A. Nardone, James B. Reuler, Donald E. Girard

Research output: Contribution to journalLetterpeer-review

6 Scopus citations


To the Editor: Ehlers-Danlos syndrome complicated by fatal intra-abdominal hemorrhage was the topic of a recent Clinicopathological Conference in the Journal (Case 3–1979). We have seen a patient who illustrated another potentially lethal complication of this connective-tissue disorder. A 28-year-old man with Ehlers-Danlos syndrome, manifested by hyperextensible joints, recurrent shoulder separations, hyper-elastic skin, easy bruisability, epicanthal folds, recurrent spontaneous pneumothorax, rectal prolapse and compatible family history and skin biopsy, presented with abdominal pain of acute onset. The patient was chronically constipated and, on the day of admission, was disimpacting himself with his index finger when he felt a piece of. No extract is available for articles shorter than 400 words.

Original languageEnglish (US)
Pages (from-to)863-864
Number of pages2
JournalNew England Journal of Medicine
Issue number15
StatePublished - Apr 12 1979
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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