Genetic imaging consortium for addiction medicine: From neuroimaging to genes

Scott Mackey; Kees Jan Kan; Bader Chaarani; Nelly Alia-Klein; Albert Batalla; Samantha Brooks; Janna Cousijn; Alain Dagher; Michiel de Ruiter; Sylvane Desrivieres; Sarah W. Feldstein Ewing; Rita Z. Goldstein; Anna E. Goudriaan; Mary M. Heitzeg; Kent Hutchison; Chiang Shan R. Li; Edythe D. London; Valentina Lorenzetti; Maartje Luijten; Rocio Martin-Santos; Angelica M. Morales; Martin P. Paulus; Tomas Paus; Godfrey Pearlson; Renée Schluter; Reza Momenan; Lianne Schmaal; Gunter Schumann; Rajita Sinha; Zsuzsika Sjoerds; Dan J. Stein; Elliot A. Stein; Nadia Solowij; Susan Tapert; Anne Uhlmann; Dick Veltman; Ruth van Holst; Henrik Walter; Margaret J. Wright; Murat Yucel; Deborah Yurgelun-Todd; Derrek P. Hibar; Neda Jahanshad; Paul M. Thompson; David C. Glahn; Hugh Garavan; Patricia Conrod

doi:10.1016/bs.pbr.2015.07.026

Genetic imaging consortium for addiction medicine: From neuroimaging to genes

Scott Mackey, Kees Jan Kan, Bader Chaarani, Nelly Alia-Klein, Albert Batalla, Samantha Brooks, Janna Cousijn, Alain Dagher, Michiel de Ruiter, Sylvane Desrivieres, Sarah W. Feldstein Ewing, Rita Z. Goldstein, Anna E. Goudriaan, Mary M. Heitzeg, Kent Hutchison, Chiang Shan R. Li, Edythe D. London, Valentina Lorenzetti, Maartje Luijten, Rocio Martin-SantosAngelica M. Morales, Martin P. Paulus, Tomas Paus, Godfrey Pearlson, Renée Schluter, Reza Momenan, Lianne Schmaal, Gunter Schumann, Rajita Sinha, Zsuzsika Sjoerds, Dan J. Stein, Elliot A. Stein, Nadia Solowij, Susan Tapert, Anne Uhlmann, Dick Veltman, Ruth van Holst, Henrik Walter, Margaret J. Wright, Murat Yucel, Deborah Yurgelun-Todd, Derrek P. Hibar, Neda Jahanshad, Paul M. Thompson, David C. Glahn, Hugh Garavan, Patricia Conrod

Psychiatry

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

21 Scopus citations

Abstract

Since the sample size of a typical neuroimaging study lacks sufficient statistical power to explore unknown genomic associations with brain phenotypes, several international genetic imaging consortia have been organized in recent years to pool data across sites. The challenges and achievements of these consortia are considered here with the goal of leveraging these resources to study addiction.The authors of this review have joined together to form an Addiction working group within the framework of the ENIGMA project, a meta-analytic approach to multisite genetic imaging data. Collectively, the Addiction working group possesses neuroimaging and genomic data obtained from over 10,000 subjects. The deadline for contributing data to the first round of analyses occurred at the beginning of May 2015. The studies performed on this data should significantly impact our understanding of the genetic and neurobiological basis of addiction.

Original language	English (US)
Title of host publication	Neuroscience for Addiction Medicine
Subtitle of host publication	From Prevention to Rehabilitation - Methods and Interventions, 2016
Editors	Hamed Ekhtiari, Martin P. Paulus
Publisher	Elsevier B.V.
Pages	203-223
Number of pages	21
ISBN (Print)	9780444637161
DOIs	https://doi.org/10.1016/bs.pbr.2015.07.026
State	Published - 2016

Publication series

Name	Progress in Brain Research
Volume	224
ISSN (Print)	0079-6123
ISSN (Electronic)	1875-7855

Keywords

Addiction
ENIGMA
Genetic imaging
Neuroimaging

ASJC Scopus subject areas

General Neuroscience

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10.1016/bs.pbr.2015.07.026

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Mackey, S., Kan, K. J., Chaarani, B., Alia-Klein, N., Batalla, A., Brooks, S., Cousijn, J., Dagher, A., de Ruiter, M., Desrivieres, S., Feldstein Ewing, S. W., Goldstein, R. Z., Goudriaan, A. E., Heitzeg, M. M., Hutchison, K., Li, C. S. R., London, E. D., Lorenzetti, V., Luijten, M., ... Conrod, P. (2016). Genetic imaging consortium for addiction medicine: From neuroimaging to genes. In H. Ekhtiari, & M. P. Paulus (Eds.), Neuroscience for Addiction Medicine: From Prevention to Rehabilitation - Methods and Interventions, 2016 (pp. 203-223). (Progress in Brain Research; Vol. 224). Elsevier B.V.. https://doi.org/10.1016/bs.pbr.2015.07.026

Genetic imaging consortium for addiction medicine: From neuroimaging to genes. / Mackey, Scott; Kan, Kees Jan; Chaarani, Bader et al.
Neuroscience for Addiction Medicine: From Prevention to Rehabilitation - Methods and Interventions, 2016. ed. / Hamed Ekhtiari; Martin P. Paulus. Elsevier B.V., 2016. p. 203-223 (Progress in Brain Research; Vol. 224).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Mackey, S, Kan, KJ, Chaarani, B, Alia-Klein, N, Batalla, A, Brooks, S, Cousijn, J, Dagher, A, de Ruiter, M, Desrivieres, S, Feldstein Ewing, SW, Goldstein, RZ, Goudriaan, AE, Heitzeg, MM, Hutchison, K, Li, CSR, London, ED, Lorenzetti, V, Luijten, M, Martin-Santos, R, Morales, AM, Paulus, MP, Paus, T, Pearlson, G, Schluter, R, Momenan, R, Schmaal, L, Schumann, G, Sinha, R, Sjoerds, Z, Stein, DJ, Stein, EA, Solowij, N, Tapert, S, Uhlmann, A, Veltman, D, van Holst, R, Walter, H, Wright, MJ, Yucel, M, Yurgelun-Todd, D, Hibar, DP, Jahanshad, N, Thompson, PM, Glahn, DC, Garavan, H & Conrod, P 2016, Genetic imaging consortium for addiction medicine: From neuroimaging to genes. in H Ekhtiari & MP Paulus (eds), Neuroscience for Addiction Medicine: From Prevention to Rehabilitation - Methods and Interventions, 2016. Progress in Brain Research, vol. 224, Elsevier B.V., pp. 203-223. https://doi.org/10.1016/bs.pbr.2015.07.026

Mackey S, Kan KJ, Chaarani B, Alia-Klein N, Batalla A, Brooks S et al. Genetic imaging consortium for addiction medicine: From neuroimaging to genes. In Ekhtiari H, Paulus MP, editors, Neuroscience for Addiction Medicine: From Prevention to Rehabilitation - Methods and Interventions, 2016. Elsevier B.V. 2016. p. 203-223. (Progress in Brain Research). doi: 10.1016/bs.pbr.2015.07.026

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title = "Genetic imaging consortium for addiction medicine: From neuroimaging to genes",

abstract = "Since the sample size of a typical neuroimaging study lacks sufficient statistical power to explore unknown genomic associations with brain phenotypes, several international genetic imaging consortia have been organized in recent years to pool data across sites. The challenges and achievements of these consortia are considered here with the goal of leveraging these resources to study addiction.The authors of this review have joined together to form an Addiction working group within the framework of the ENIGMA project, a meta-analytic approach to multisite genetic imaging data. Collectively, the Addiction working group possesses neuroimaging and genomic data obtained from over 10,000 subjects. The deadline for contributing data to the first round of analyses occurred at the beginning of May 2015. The studies performed on this data should significantly impact our understanding of the genetic and neurobiological basis of addiction.",

keywords = "Addiction, ENIGMA, Genetic imaging, Neuroimaging",

author = "Scott Mackey and Kan, {Kees Jan} and Bader Chaarani and Nelly Alia-Klein and Albert Batalla and Samantha Brooks and Janna Cousijn and Alain Dagher and {de Ruiter}, Michiel and Sylvane Desrivieres and {Feldstein Ewing}, {Sarah W.} and Goldstein, {Rita Z.} and Goudriaan, {Anna E.} and Heitzeg, {Mary M.} and Kent Hutchison and Li, {Chiang Shan R.} and London, {Edythe D.} and Valentina Lorenzetti and Maartje Luijten and Rocio Martin-Santos and Morales, {Angelica M.} and Paulus, {Martin P.} and Tomas Paus and Godfrey Pearlson and Ren{\'e}e Schluter and Reza Momenan and Lianne Schmaal and Gunter Schumann and Rajita Sinha and Zsuzsika Sjoerds and Stein, {Dan J.} and Stein, {Elliot A.} and Nadia Solowij and Susan Tapert and Anne Uhlmann and Dick Veltman and {van Holst}, Ruth and Henrik Walter and Wright, {Margaret J.} and Murat Yucel and Deborah Yurgelun-Todd and Hibar, {Derrek P.} and Neda Jahanshad and Thompson, {Paul M.} and Glahn, {David C.} and Hugh Garavan and Patricia Conrod",

note = "Funding Information: This work was supported by a National Institute on Drug Abuse (NIDA) Grant 1R21DA038381 and by a National Institutes of Health (NIH) Grant U54 EB 020403 with funds provided for the trans-NIH Big Data to Knowledge (BD2K) initiative. Support was also provided by an NIH Grant 1P20GM103644-01A1 awarded to the Vermont Center on Behavior and Health.",

year = "2016",

doi = "10.1016/bs.pbr.2015.07.026",

language = "English (US)",

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AU - Batalla, Albert

AU - Brooks, Samantha

AU - Cousijn, Janna

AU - Dagher, Alain

AU - de Ruiter, Michiel

AU - Desrivieres, Sylvane

AU - Feldstein Ewing, Sarah W.

AU - Goldstein, Rita Z.

AU - Goudriaan, Anna E.

AU - Heitzeg, Mary M.

AU - Hutchison, Kent

AU - Li, Chiang Shan R.

AU - London, Edythe D.

AU - Lorenzetti, Valentina

AU - Luijten, Maartje

AU - Martin-Santos, Rocio

AU - Morales, Angelica M.

AU - Paulus, Martin P.

AU - Paus, Tomas

AU - Pearlson, Godfrey

AU - Schluter, Renée

AU - Momenan, Reza

AU - Schmaal, Lianne

AU - Schumann, Gunter

AU - Sinha, Rajita

AU - Sjoerds, Zsuzsika

AU - Stein, Dan J.

AU - Stein, Elliot A.

AU - Solowij, Nadia

AU - Tapert, Susan

AU - Uhlmann, Anne

AU - Veltman, Dick

AU - van Holst, Ruth

AU - Walter, Henrik

AU - Wright, Margaret J.

AU - Yucel, Murat

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AU - Thompson, Paul M.

AU - Glahn, David C.

AU - Garavan, Hugh

AU - Conrod, Patricia

N1 - Funding Information: This work was supported by a National Institute on Drug Abuse (NIDA) Grant 1R21DA038381 and by a National Institutes of Health (NIH) Grant U54 EB 020403 with funds provided for the trans-NIH Big Data to Knowledge (BD2K) initiative. Support was also provided by an NIH Grant 1P20GM103644-01A1 awarded to the Vermont Center on Behavior and Health.

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ER -

Genetic imaging consortium for addiction medicine: From neuroimaging to genes

Abstract

Publication series

Keywords

ASJC Scopus subject areas

Access to Document

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