Genicular Artery Embolization for Primary Knee Osteoarthritis

Ravi Tyagi, S. Samaduddin Ahmed, Yilun Koethe, Aleksandr Raskind, Osman Ahmed

Research output: Contribution to journalArticlepeer-review


Genicular artery embolization (GAE) is a novel treatment for knee osteoarthritis (OA) with increasing interest and utilization worldwide. The genicular arteries are selectively embolized using microspheres with subsequent cessation of abnormal synovial hyperemia, a process believed to arrest the inflammatory changes and pain associated with OA. Current data indicate that GAE offers sustained, 6-month improvement in Western Ontario and McMaster Universities Osteoarthritis index (WOMAC) and visual analog scale scores in 80 to 85% of patients with mild to moderate OA. As GAE gains traction, future studies are needed to establish its safety and efficacy relative to placebo and other standard-of-care therapies while also characterizing populations for which it is most effective.

Original languageEnglish (US)
Pages (from-to)125-129
Number of pages5
JournalSeminars in Interventional Radiology
Issue number2
StatePublished - Apr 1 2022


  • GAE
  • VAS
  • embolization
  • genicular artery embolization
  • interventional radiology
  • osteoarthritis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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