Graphical and stereolithographic models of the developing human heart lumen

J. O. Pentecost; D. J. Sahn; B. L. Thornburg; M. Gharib; A. Baptista; K. L. Thornburg

doi:10.1016/S0895-6111(01)00020-9

Graphical and stereolithographic models of the developing human heart lumen

J. O. Pentecost, D. J. Sahn, B. L. Thornburg, M. Gharib, A. Baptista, K. L. Thornburg

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Scaled physical models can be useful in analyzing stage-specific hemodynamics in the embryonic human heart to address correlations between early physical stressors and myocardial wall responses. We generated models of the cardiac blood space from reconstructions of four digitized human embryo images from Carnegie Collection at the Armed Forces Institute of Pathology. From physical scale models manufactured by stereolithography, compliant sleeves can be created for flow dynamics studies. This novel use of Carnegie collection images and graphical modeling software provides tools for broadening our understanding of normal and aberrant heart formation.

Original language	English (US)
Pages (from-to)	459-463
Number of pages	5
Journal	Computerized Medical Imaging and Graphics
Volume	25
Issue number	6
DOIs	https://doi.org/10.1016/S0895-6111(01)00020-9
State	Published - 2001

Keywords

3D modeling
CFD
Cardiogenesis
Embryo
Graphical models
Heart
Human

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging
Computer Vision and Pattern Recognition
Health Informatics
Computer Graphics and Computer-Aided Design

Access to Document

10.1016/S0895-6111(01)00020-9

Cite this

@article{dfa8d907bec2401dba2a7e9d551aeb6d,

title = "Graphical and stereolithographic models of the developing human heart lumen",

abstract = "Scaled physical models can be useful in analyzing stage-specific hemodynamics in the embryonic human heart to address correlations between early physical stressors and myocardial wall responses. We generated models of the cardiac blood space from reconstructions of four digitized human embryo images from Carnegie Collection at the Armed Forces Institute of Pathology. From physical scale models manufactured by stereolithography, compliant sleeves can be created for flow dynamics studies. This novel use of Carnegie collection images and graphical modeling software provides tools for broadening our understanding of normal and aberrant heart formation.",

keywords = "3D modeling, CFD, Cardiogenesis, Embryo, Graphical models, Heart, Human",

author = "Pentecost, {J. O.} and Sahn, {D. J.} and Thornburg, {B. L.} and M. Gharib and A. Baptista and Thornburg, {K. L.}",

note = "Funding Information: This project was funded by a grant from The Children's Heart Foundation, Chicago. ",

year = "2001",

doi = "10.1016/S0895-6111(01)00020-9",

language = "English (US)",

volume = "25",

pages = "459--463",

journal = "Computerized Medical Imaging and Graphics",

issn = "0895-6111",

publisher = "Elsevier Limited",

number = "6",

}

TY - JOUR

T1 - Graphical and stereolithographic models of the developing human heart lumen

AU - Pentecost, J. O.

AU - Sahn, D. J.

AU - Thornburg, B. L.

AU - Gharib, M.

AU - Baptista, A.

AU - Thornburg, K. L.

N1 - Funding Information: This project was funded by a grant from The Children's Heart Foundation, Chicago.

PY - 2001

Y1 - 2001

N2 - Scaled physical models can be useful in analyzing stage-specific hemodynamics in the embryonic human heart to address correlations between early physical stressors and myocardial wall responses. We generated models of the cardiac blood space from reconstructions of four digitized human embryo images from Carnegie Collection at the Armed Forces Institute of Pathology. From physical scale models manufactured by stereolithography, compliant sleeves can be created for flow dynamics studies. This novel use of Carnegie collection images and graphical modeling software provides tools for broadening our understanding of normal and aberrant heart formation.

AB - Scaled physical models can be useful in analyzing stage-specific hemodynamics in the embryonic human heart to address correlations between early physical stressors and myocardial wall responses. We generated models of the cardiac blood space from reconstructions of four digitized human embryo images from Carnegie Collection at the Armed Forces Institute of Pathology. From physical scale models manufactured by stereolithography, compliant sleeves can be created for flow dynamics studies. This novel use of Carnegie collection images and graphical modeling software provides tools for broadening our understanding of normal and aberrant heart formation.

KW - 3D modeling

KW - CFD

KW - Cardiogenesis

KW - Embryo

KW - Graphical models

KW - Heart

KW - Human

UR - http://www.scopus.com/inward/record.url?scp=0034773325&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034773325&partnerID=8YFLogxK

U2 - 10.1016/S0895-6111(01)00020-9

DO - 10.1016/S0895-6111(01)00020-9

M3 - Article

C2 - 11679207

AN - SCOPUS:0034773325

SN - 0895-6111

VL - 25

SP - 459

EP - 463

JO - Computerized Medical Imaging and Graphics

JF - Computerized Medical Imaging and Graphics

IS - 6

ER -

Graphical and stereolithographic models of the developing human heart lumen

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this