Abstract
Late hemorrhagic disease of the newborn (HDN) presents 0.5-6 months after birth with mucocutaneous and intracranial bleeding. We describe here two cases of late HDN in infants who received vitamin K. The first case is a previously healthy breastfed male who received one dose of oral vitamin K at birth and developed an intracranial hemorrhage 5 weeks later. He was treated with intravenous vitamin K and recombinant factor VIIa prior to emergent craniectomy. An unrelated infant presented at 5 months of age with diarrhea and easy bruising despite IM vitamin K at birth. These cases illustrate the morbidity associated with late HDN.
Original language | English (US) |
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Pages (from-to) | 1075-1077 |
Number of pages | 3 |
Journal | Pediatric Blood and Cancer |
Volume | 50 |
Issue number | 5 |
DOIs | |
State | Published - May 2008 |
Keywords
- Bleeding disorders
- Esp. in newborns
- Intracranial hemorrhage
- Vitamin K
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Hematology
- Oncology