Hepatic Encephalopathy

Yasemen Eroglu, William J. Byrne

Research output: Contribution to journalReview articlepeer-review

41 Scopus citations


Hepatic encephalopathy is characterized by a wide spectrum of neuropsychiatric abnormalities and motor disturbances in patients with advanced liver disease. It is estimated to occur in 30% to 45% of patients with liver cirrhosis and in 10% to 50% of patients with transjugular intrahepatic portosystemic shunts. It can be seen in cancer patients due to multiple factors. Early diagnosis and treatment are important but can be challenging, especially in mild forms with subtle findings. This article reviews the pathogenesis, diagnostic criteria, grading, and management of hepatic encephalopathy.

Original languageEnglish (US)
Pages (from-to)401-414
Number of pages14
JournalEmergency Medicine Clinics of North America
Issue number3
StatePublished - Aug 2009
Externally publishedYes


  • Brain edema
  • Cancer
  • Emergency department
  • Encephalopathy
  • Liver
  • Liver failure

ASJC Scopus subject areas

  • Emergency Medicine


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