Hepatic thrombopoietin gene silencing reduces platelet count and breast cancer progression in transgenic MMTV-PyMT mice

Medicine & Life Sciences

• Alveolar Macrophages 6%
• Blood Platelets 24%
• Bone Marrow 4%
• Breast Neoplasms 47%
• Euthanasia 7%
• Gene Expression 3%
• Gene Silencing 78%
• Genes 17%
• Growth 3%
• Hemostasis 6%
• Hemostatics 19%
• Intercellular Signaling Peptides and Proteins 5%
• Leukemia 5%
• Liver 38%
• Megakaryocytes 14%
• Mental Competency 5%
• Neoplasm Metastasis 3%
• Neoplasms 1%
• Neoplastic Processes 8%
• Oncogenes 5%
• Papio 7%
• Pathologic Processes 6%
• Pathology 3%
• Pharmacology 4%
• Platelet Count 71%
• Platelet Factor 4 8%
• Primates 5%
• Reference Values 4%
• Therapeutics 1%
• Thrombopoietin 100%
• Thrombosis 4%
• Tumor Burden 5%
• Vascular Endothelial Growth Factor A 5%
• Viruses 4%