Hepatotoxicity associated with use of D-penicillamine in rheumatoid arthritis

J. Rosenbaum, W. A. Katz, H. R. Schumacher

Research output: Contribution to journalArticlepeer-review


Two patients with rheumatoid arthritis developed evidence of hepatotoxicity while receiving D-penicillamine. Both recovered after withdrawal of the drug. These cases and a review of the literature suggested that hepatotoxicity, though rare, should be added to the list of adverse reactions to D-penicillamine.

Original languageEnglish (US)
Pages (from-to)152-154
Number of pages3
JournalAnnals of the rheumatic diseases
Issue number2
StatePublished - 1980
Externally publishedYes

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology
  • Biochemistry, Genetics and Molecular Biology(all)


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