@article{80874cf66148495f9f795d549c5e36d6,
title = "HIV infection and arterial stiffness among older-adults taking antiretroviral therapy in rural Uganda",
abstract = "HIV infection is associated with arterial stiffness, but no studies have assessed this relationship in sub-Saharan Africa. We enrolled 205 participants over 40 years old in Uganda: 105 on antiretroviral therapy for a median of 7 years, and a random sample of 100 age and sex-matched HIV-uninfected controls from the clinic catchment area. The prevalence of arterial stiffness (ankle brachial index >1.2) was 33%, 18%, 19% and 2% in HIV+ men, HIV-men, HIV+ women, and HIV-women. In multivariable models adjusted for cardiovascular risk factors, HIV+ individuals had over double the prevalence of arterial stiffness (adjusted prevalence ratio 2.86, 95% confidence interval 1.41-5.79, P=0.003).",
author = "Siedner, {Mark J.} and Kim, {June Ho} and Nakku, {Ruth Sentongo} and Linda Hemphill and Triant, {Virginia A.} and Haberer, {Jessica E.} and Martin, {Jeffrey N.} and Yap Boum and Kwon, {Douglas S.} and Tsai, {Alexander C.} and Hunt, {Peter W.} and Samson Okello and Bangsberg, {David R.}",
note = "Funding Information: Funding: This study was funded by the National Institutes of Health (R21HL124712, K23MH099916, R56AI100765, R21AI078774, R01MH054907, P01AI027763, P01AI076174 and UM1 CA181255), the Harvard Center for AIDS Research, the Doris Duke Charitable Foundation, and the Sullivan Family Foundation. The authors also acknowledge salary support through K23MH096620. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Author roles: Study design and data collection: M.J.S., J.H.K., R.S., L.H., V.A.T., J.E.H., J.N.M., Y.B., D.S.K., A.C.T., W.H., S.O., D.R.B. Data analysis and interpretation: M.J.S. Composed first draft of manuscript: M.J.S. Contributed significant editorial input to manuscript: J.H.K., R.S., L.H., V.A.T., J.E.H., J.N.M., Y.B., D.S.K., A.C.T., W.H., S.O., D.R.B. Approve of the final version of the manuscript: M.J.S., J.H.K., R.S., L.H., V.A.T., J.E.H., J.N.M., Y.B., D.S.K., A.C.T.,W.H., S.O., D.R.B. Presentation: This work was presented in part at the 2015 International AIDS Conference in Vancouver, Canada. Publisher Copyright: {\textcopyright} 2016 Wolters Kluwer Health, Inc.",
year = "2016",
month = feb,
day = "20",
doi = "10.1097/QAD.0000000000000992",
language = "English (US)",
volume = "30",
pages = "667--670",
journal = "AIDS",
issn = "0269-9370",
publisher = "Lippincott Williams and Wilkins",
number = "4",
}