Hospitalization costs associated with bronchopulmonary dysplasia in the first year of life

Wannasiri Lapcharoensap, Mihoko V. Bennett, Xiao Xu, Henry C. Lee, Dmitry Dukhovny

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


Objective: To determine costs of hospitalization associated with bronchopulmonary dysplasia (BPD) during the first year in very low birth weight infants. Study design: Retrospective cohort study of California births from 2008 to 2011 linking birth certificate, discharge records, and clinical data from California Perinatal Quality Care Collaborative. Inclusion: birth weight 401–1500 g, gestational age < 30 weeks, inborn or transferred within 2 days, alive at 36 weeks corrected, and without major congenital anomalies. Outcomes included cost and length of stay of initial hospitalization and rehospitalizations. Result: Out of 7998 eligible infants, 2696 (33.7%) developed BPD. Median hospitalization cost in the first year was $377,871 per infant with BPD compared with $175,836 per infant without BPD (adjusted cost ratio 1.54, 95% confidence interval (CI) 1.49–1.59). Infants with BPD also had longer length of stay and a higher likelihood of rehospitalization. Conclusion: BPD is associated with substantial resource utilization. Prevention strategies could help conserve healthcare resources.

Original languageEnglish (US)
Pages (from-to)130-137
Number of pages8
JournalJournal of Perinatology
Issue number1
StatePublished - Jan 1 2020

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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