Hyperparathyroidism and intracerebral calcification

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Bilateral basal ganglia calcification was noted in 2 patients with primary nonfamilial hyperparathyroidism and very similar neurological syndromes. Neurologic abnormalities consisted primarily of parkinsonian features, gait apraxia and frontal lobe dysfunction. In 1 patient, parathyroidectomy was followed by distinct neurological improvement and the virtual disappearance of intracranial calcification. Parathyroid hormone has effects on neurological function and brain calcium content, and may result in clinically significant but reversible basal ganglia calcification.

Original languageEnglish (US)
Pages (from-to)273-279
Number of pages7
JournalMineral and Electrolyte Metabolism
Issue number6
StatePublished - 1981

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry


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