Hypertrophic cardiomyopathy: Contemporary evaluation and management

Hypertrophic cardiomyopathy (HCM) is the most common monogenetic hereditary heart disease. With advances in cardiac imaging and genetics, an increasing number of patients with HCM are being identified. However, the condition remains underrecognized, largely because its clinical manifestations are unpredictable and vary among individuals even within the same family. The presentation ranges from sudden cardiac death to a completely benign course with no morbidity or impact on longevity. The overall prognosis of HCM is excellent, but it is this unpredictability that makes the diagnosis and management challenging, requiring a multifaceted approach.