Identification and Significance of Multinucleate Tumor Cells In Retinoblastoma

Martha A. Howard; Thaddeus P. Dryja; Daniel M. Albert; David S. Walton

doi:10.1001/archopht.1989.01070020087037

Identification and Significance of Multinucleate Tumor Cells In Retinoblastoma

Martha A. Howard, Thaddeus P. Dryja, Daniel M. Albert, David S. Walton

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Multinucleate tumor cells were observed in a case of a retinal tumor suspected to be a retinoma (retinocytoma). On electron microscopy, these cells had characteristics of retinoblastoma. Similar cells were observed in an irradiated model of retinoblastoma grown in a nude mouse. We suggest that the presence of these cells indicates differentiation and/or regression of the tumor.

Original language	English (US)
Pages (from-to)	1025-1030
Number of pages	6
Journal	Archives of ophthalmology
Volume	107
Issue number	7
DOIs	https://doi.org/10.1001/archopht.1989.01070020087037
State	Published - Jul 1989
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology

Access to Document

10.1001/archopht.1989.01070020087037

Cite this

@article{1d196bec75d64f20a2243cc4faec0fa7,

title = "Identification and Significance of Multinucleate Tumor Cells In Retinoblastoma",

abstract = "Multinucleate tumor cells were observed in a case of a retinal tumor suspected to be a retinoma (retinocytoma). On electron microscopy, these cells had characteristics of retinoblastoma. Similar cells were observed in an irradiated model of retinoblastoma grown in a nude mouse. We suggest that the presence of these cells indicates differentiation and/or regression of the tumor.",

author = "Howard, {Martha A.} and Dryja, {Thaddeus P.} and Albert, {Daniel M.} and Walton, {David S.}",

year = "1989",

month = jul,

doi = "10.1001/archopht.1989.01070020087037",

language = "English (US)",

volume = "107",

pages = "1025--1030",

journal = "JAMA Ophthalmology",

issn = "2168-6165",

publisher = "American Medical Association",

number = "7",

}

TY - JOUR

T1 - Identification and Significance of Multinucleate Tumor Cells In Retinoblastoma

AU - Howard, Martha A.

AU - Dryja, Thaddeus P.

AU - Albert, Daniel M.

AU - Walton, David S.

PY - 1989/7

Y1 - 1989/7

N2 - Multinucleate tumor cells were observed in a case of a retinal tumor suspected to be a retinoma (retinocytoma). On electron microscopy, these cells had characteristics of retinoblastoma. Similar cells were observed in an irradiated model of retinoblastoma grown in a nude mouse. We suggest that the presence of these cells indicates differentiation and/or regression of the tumor.

AB - Multinucleate tumor cells were observed in a case of a retinal tumor suspected to be a retinoma (retinocytoma). On electron microscopy, these cells had characteristics of retinoblastoma. Similar cells were observed in an irradiated model of retinoblastoma grown in a nude mouse. We suggest that the presence of these cells indicates differentiation and/or regression of the tumor.

UR - http://www.scopus.com/inward/record.url?scp=0024413877&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024413877&partnerID=8YFLogxK

U2 - 10.1001/archopht.1989.01070020087037

DO - 10.1001/archopht.1989.01070020087037

M3 - Article

C2 - 2751457

AN - SCOPUS:0024413877

SN - 2168-6165

VL - 107

SP - 1025

EP - 1030

JO - JAMA Ophthalmology

JF - JAMA Ophthalmology

IS - 7

ER -

Identification and Significance of Multinucleate Tumor Cells In Retinoblastoma

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this