Idiopathic myelofibrosis: dental treatment considerations

Robert Steelman, Douglas Holmes, Roberta Cranston, Dolly Cupp

Research output: Contribution to journalArticlepeer-review


Idiopathic myelofibrosis is a myeloproliferative disorder of unknown origin. The bone marrow becomes fibrotic with an associated decrease in hematopoiesis resulting in anemia, bleeding problems, splenomegaly, and other secondary abnormalities. Although idiopathic myelofibrosis is usually diagnosed in middle age, there have been a few reports of the disorder in the pediatric population. This case report documents dental treatment considerations in a 6‐year‐old female with idiopathic myelofibrosis, severe anemia, and abnormal blood coagulation studies. The patient was successfully treated in a hospital after medical consultation, transfusion of packed red blood cells, and administration of prophylactic antibiotics. Local hemostatic measures following multiple extractions of carious teeth controlled bleeding. No postoperative sequelae occurred.

Original languageEnglish (US)
Pages (from-to)68-70
Number of pages3
JournalSpecial Care in Dentistry
Issue number2
StatePublished - Mar 1991
Externally publishedYes

ASJC Scopus subject areas

  • Dentistry(all)


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