Imaging Genomics

Cymon N. Kersch; Ramon F. Barajas

doi:10.1007/978-3-030-27359-0_14

Imaging Genomics

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Imaging genomics studies the relationship of clinical imaging features with genomic/molecular characteristics and has great potential to improve the diagnosis, treatment planning, and monitoring of patients with glioblastoma (GBM). While still a relatively young field, imaging genomics has made significant progress over the past decade. Here, we review clinically relevant genomic and molecular features of GBM, briefly describe MRI techniques with utility in the evaluation of GBM, and provide an overview of imaging genomics applications in the development of biomarkers of molecular tumor characteristics. Lastly we discuss how this approach can be leveraged to improve characterization of entire tumors throughout a patient’s treatment course in a non-invasive manner.

Original language	English (US)
Title of host publication	Glioma Imaging
Subtitle of host publication	Physiologic, Metabolic, and Molecular Approaches
Publisher	Springer International Publishing
Pages	223-239
Number of pages	17
ISBN (Electronic)	9783030273590
ISBN (Print)	9783030273583
DOIs	https://doi.org/10.1007/978-3-030-27359-0_14
State	Published - Jan 1 2019

Keywords

GBM
Glioblastoma
Glioma
Imaging genomics
MRI
Magnetic resonance imaging
Radiogenomics
Radiophenotype

ASJC Scopus subject areas

General Medicine
General Biochemistry, Genetics and Molecular Biology

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10.1007/978-3-030-27359-0_14

Cite this

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KW - MRI

KW - Magnetic resonance imaging

KW - Radiogenomics

KW - Radiophenotype

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Imaging Genomics

Abstract

Keywords

ASJC Scopus subject areas

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